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Dornase alfa | compare suppliers & send inquiries for free

Here you will find a list of producers, manufacturers and traders of Dornase alfa. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.

Type: Producer
Origin: United States
United States
Speranza Chemical Co.,Ltd

MOQ: 1 kg
Type: Producer
Origin: China
Bbi Enzymes

Type: Producer
Origin: South Africa
South Africa

Looking for Dornase alfa 143831-71-4?

API | Excipient name:
Dornase alfa 
Deoxyribonuclease (human clone 18-1 protein moiety), Dornase alfa, recombinant, Dornase alpha, Recombinant deoxyribonuclease (DNAse), Deoxyribonuclease  
Cas Number:
DrugBank number:
Unique Ingredient Identifier:

About Dornase alfa

Why are professionals looking for Dornase alfa? Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products without affecting intracellular DNA.

In individuals with cystic fibrosis, extracellular DNA, which is an extremely viscous anion, is released by degenerating leukocytes that accumulate during inflammatory responses to infections. Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity.

Ask the supplier for a certificate of analysis to find out more about the quality of Dornase alfa.

Dornase alfa manufacturers | traders | suppliers
We have 3 companies offering Dornase alfa from 3 different countries.

Get in contact with the supplier of your choice:

  • Speranza Chemical Co.,Ltd from China
  • Sigma-Aldrich from United States
  • Bbi Enzymes from South Africa

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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