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Glucarpidase | compare suppliers & send inquiries for free

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United States Sigma-Aldrich
Type: Producer
Produced in: United States
United States

Looking for Glucarpidase 9074-87-7?

API | Excipient name:
Folate hydrolase G2, Glutamate carboxypeptidase  
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About Glucarpidase

It's time for some technical information for the ones who understand chemistry: Glucarpidase is the recombinant form of the Pseudomonas sp. (strain RS-16) enzyme carboxypeptidase G2 that is produced in Escherichia coli. In patients, glucarpidase inactivates methotrexate, and other antifolates, by hydrolyzing glutamate on the carboxyl terminal of these compounds. Therefore since methotrexate is eliminated enzymatically and not by the kidneys, glucarpidase is indicated in patients on methotrexate treatment who have kidney dysfunction, and are experiencing an abnormally high plasma concentration of methotrexate (<1 micromole per liter).

Glucarpidase is marketed under the brand name Voraxaze®.

You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet and DMF.

Glucarpidase manufacturers | traders | suppliers
We have 1 companies offering Glucarpidase from 1 different countries.

Get in contact with the supplier of your choice:

  • Sigma-Aldrich from United States

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