Pimavanserin | compare suppliers & send inquiries for free
Shandong Octagon Chemicals Limited
MOQ: 1 g
MOQ: 1 kg
MSN Life Sciences
Looking for Pimavanserin 706779-91-1?
Learn more about Pimavanserin. Pimavanserin (ACP-103), marketed under the trade name Nuplazid, is a drug developed by Acadia Pharmaceuticals which acts as an inverse agonist on the serotonin receptor subtype 5-HT2A, with 40x selectivity over 5-HT2C, and no significant affinity or activity at 5-HT2B or dopamine receptors. As of September 2009, pimavanserin has not met expectations for Phase III clinical trials for the treatment of Parkinson's disease psychosis. It is in Phase II trials for adjunctive treatment of schizophrenia alongside an antipsychotic medication and is expected to improve the effectiveness and side effect profile of antipsychotics.
The results of a clinical trial examining the efficacy, tolerability and safety of adjunctive pimavanserin to risperidone and haloperidol were published in November 2012 and the results showed that pimavanserin potentiated the antipsychotic effects of subtherapeutic doses of risperidone and improve the tolerability of haloperidol treatment by reducing the incidence of extrapyramidal symptoms. On September 2014, the United States Food and Drug administration granted Breakthrough Therapy status to Acadia's New Drug Application for pimavanserin.
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Pimavanserin manufacturers | traders | suppliers
We have 4 companies offering Pimavanserin from 3 different countries.
Get in contact with the supplier of your choice:
- Shandong Octagon Chemicals Limited from China
- Bayee Biotech(Anqing)Co.,Ltd from China
- Polpharma from Poland
- MSN Life Sciences from India
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