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Protriptyline | compare suppliers & send inquiries for free

Here you will find a list of producers, manufacturers and traders of Protriptyline. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
Emcure Pharma


Type: Producer
Origin: India
India
Olon


Type: Producer
Origin: Italy
Italy
Dipharma Francis S.r.l.


Type: Producer
Origin: Italy
Italy

Looking for Protriptyline 438-60-8?

API | Excipient name:
Protriptyline 
Synonyms:
Amimetilina, Protriptilina, Protriptylin, Protriptyline, Protriptylinum  
Cas Number:
438-60-8 
DrugBank number:
DB00344 
Unique Ingredient Identifier:
4NDU154T12

About Protriptyline

What makes Protriptyline unique? Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation.

In depressed individuals, protriptyline exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. In addition, TCAs down-regulate cerebral cortical β-adrenergic receptors and sensitize post-synaptic serotonergic receptors with chronic use. The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. TCAs also block histamine H1 receptors, alpha1-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred vision, dry mouth, constipation, urinary retention), respectively. See toxicity section below for a complete listing of side effects. Protriptyline may be used for the treatment of depression.

You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet and DMF.

Protriptyline manufacturers | traders | suppliers
We have 3 companies offering Protriptyline from 2 different countries.

Get in contact with the supplier of your choice:

  • Emcure Pharma from India
  • Olon from Italy
  • Dipharma Francis S.r.l. from Italy

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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