Priya Bhat | Posted on March 23, 2023

 Top 10 most popular APIs on Pharmaoffer


Medicines are indispensable in our lives; they can cure, prevent or ease symptoms, making our lives longer and easier. While most of us think of pills or syrup when thinking of medicine, they are almost always composed of two different ingredients; the API and the excipient. 

API is short for Active Pharmaceutical Ingredients; it is the substance in the medicine that does the actual healing. Without the API, we will swallow pills and wait for an effect that will never arrive. On the other hand, the excipient makes the drug at least bearable to consume. For instance, it can be what alters the shape, the taste, and the color. 


If you want to learn more about APIs, you can check our recent blogs, where we give more detailed information. 

Now that we know what APIs are, we should also explain that entire companies are dedicated to producing these APIs. After all, it is a complicated and strictly regulated process for an industry worth multi-billion dollars. 

Our platform Pharmaoffer is dedicated to APIs only. Every day, suppliers and buyers from different companies from all parts of the world communicate on our platform to buy or sell APIs. We love to facilitate this process for them. And it also makes us quite aware of the recent API trends and data. We can see which APIs are the most popular for specific periods or geographical areas. 


In this article, we want to share some of that knowledge and list the most popular APIs on our platform from March 2022 until March 2023. And no worries, we will explain those APIs since we assume that they will sound like gibberish to anyone who doesn’t have a pharmaceutical degree. 


10. Sitagliptin

Sitagliptin has become increasingly popular due to its cost-effectiveness, ease of use, and effectiveness in treating type 2 diabetes. Sitagliptin helps to control blood sugar levels by increasing substances in the body that make the pancreas release more insulin. It is usually available in tablet forms. Furthermore, it has few side effects; and the most common side effect is headaches. Sitagliptin oral tablet is known by the brand-name of Januvia.

9. Levothyroxine

Levothyroxine is an active pharmaceutical ingredient (API) used to treat hypothyroidism and other thyroid-related conditions. It helps the body maintain normal hormone levels essential for proper metabolism. It should also be noted that Levothyroxine controls hypothyroidism but does not cure it. It may take several weeks before you notice a change in your symptoms. Levothyroxine is available in various forms, including tablets, capsules, and injections. Synthroid is the general brand name for Levothyroxine, but it can also come in different other brand names. 






8. Losartan 

Losartan treats high blood pressure, heart failure, and diabetic nephropathy. It can also be used to treat kidney disease in people who have type 2 diabetes. It has been around for over two decades and is still widely prescribed by doctors. Losartan has many uses and dosages that can be tailored to each patient’s needs. The price of Losartan also varies depending on the supplier, but it remains relatively affordable compared to other APIs. Losartan is available as the brand-name drug Cozaar. It is also available as a generic drug, which is more cost-effective.

If you want to learn the difference between brand name and generic drugs, you can find a clear and detailed explanation on this blog.

7. Tramadol 

Tramadol is a powerful opioid pain reliever that is used to treat moderate to severe pain. It works by changing the way the body senses and responds to pain. Tramadol can be taken orally, as a tablet, capsule, or liquid form. The effects of Tramadol usually last 4-6 hours, depending on the dose and how it is administered.

Tramadol is available in various forms at different prices depending on the dosage strength and quantity purchased. It should only be used as directed by your doctor or pharmacist and not for recreational use. The side effects can range from mild symptoms such as nausea and headache to more serious side effects, such as confusion and seizures which require immediate medical attention. It is available under the brand names Ultram and Conzip.




 6. Amlodipine

Amlodipine is an active pharmaceutical ingredient used to treat high blood pressure. It is also used to treat certain types of angina (chest pain). It belongs to a class of drugs known as calcium channel blockers, which work by relaxing the muscles of the blood vessels, allowing them to widen and reduce the pressure on the walls. It is also used to prevent heart attacks and strokes.

Amlodipine is available in both generic and brand-name forms; the brand names of Amlodipine are Norvasc and Katerzia. 



 5. Potassium Iodide 

Potassium iodide is in a class of medications called anti-thyroid medications. Potassium iodide protects the thyroid gland from taking in radioactive iodine that may be released during a nuclear radiation emergency. It works by blocking radioactive iodine from entering the thyroid gland. You should only take potassium iodide if there is a nuclear radiation emergency and public officials tell you that you should take it. 

Potassium iodide is also sometimes used to treat overactive thyroid glands and sporotrichosis (a skin infection caused by a fungus). You can find it under brand names such as Iosat and ThyroSafe.




4. Sertraline 

Sertraline is an antidepressant, and the FDA has approved it for treating depression, obsessive-compulsive disorder, panic disorder, and post-traumatic stress disorder (PTSD). Sertraline works by increasing the amount of serotonin in the brain, which helps to improve mood and reduce anxiety. It can be taken either orally or as an injection.

Sertraline is available in a range of different strengths and prices depending on the dosage needed for each person. It is important to understand how to use Sertraline correctly in order to get the maximum benefit from it and minimize any potential side effects. In addition, it is important to be aware of any potential interactions with other medications that may occur when taking Sertraline. The brand name for Sertraline is Zoloft, but it can also be found in generic versions. 



3. Paracetamol 

Paracetamol might be the only API on this list that you are probably familiar with. It is one of the most commonly used active pharmaceutical ingredients. It is an effective pain reliever and fever reducer that is available in many brand names. Paracetamol works by reducing the production of prostaglandins, which are chemicals that cause inflammation and pain in the body. Paracetamol is generally safe to use when taken as directed, but it can have some side effects if taken in high doses or for an extended period of time. 



2. Metformin 

Metformin is one of the most popular active pharmaceutical ingredients (API) in the pharmaceutical industry. It treats type 2 diabetes, polycystic ovary syndrome, and obesity. Metformin works by decreasing the amount of glucose the liver produces and increasing insulin sensitivity in muscle cells. This helps to regulate blood sugar levels and reduce the risk of developing diabetes-related complications.

Additionally, it has fewer side effects than many other drugs available on the market today. As a result, it has become one of the most widely prescribed APIs in recent years. It is available under various brand names, such as Glucophage and Glumetza.












1. Semaglutide 

Commonly known as “the weight loss drug,” Semaglutide treats type 2 diabetes and obesity. Semaglutide helps reduce blood glucose levels, improve glycemic control, and reduce body weight. Its popularity comes from its ability to be used in combination with other drugs, making it more effective than other APIs on the market. The most common brand name for Semaglutide is Ozempic. 


This article is written to inform rather than advise and commercial purposes. It’s always a good idea to get in touch with your doctor/pharmacist if you require more information. 

We hope this article was informative enough to give you an idea of the recent API trends on Pharmaoffer.

Thank you for reading! 

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