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Located in:

India

Produced in:

India

Established in: 1984

MOQ: -

Employees: 2000+

Vertically integrated company

Largest producer of Montelukast in the world

USFDA & WHO GMP approved API plants

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Produced in:

China

Established in: 2011

MOQ: 1 kg

Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms

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Located in:

China

Passed ISO9001:2015 and SGS audit

Provide one-stop CDMO service from R&D to production

Certifications: ISO9001: 2015, HALAL Certificate, Kosher Certification

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Produced in:

Unknown

Established in: 1963

MOQ: -

Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe

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Produced in:

Unknown

Established in: 1923

MOQ: 25 kg

Employees: 20+

Service-oriented company

Global supply chain resilience

Support of your new projects from start to commercial realisation

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India

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South Korea
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China
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Located in:

India
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Japan
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China

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Producer

Produced in:

Unknown

Established in: 1944

MOQ: -

Employees: 4,000

14 international API plant sites

Portfolio of 350+ APIs

Teva is among the world’s largest generic drug/API manufacturers

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India
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India

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Located in:

Slovenia

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China
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India
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Hungary

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Located in:

India
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Located in:

China

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China
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Produced in:

India

Established in: 1994

MOQ: -

Employees: 4,000

All our 5 plants are top notch and FDA approved

We are a backwards integrated company

We have received 24 CEP’s and 27 USDMF’s

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Located in:

Germany

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Located in:

Japan
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Spain

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Located in:

India
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Located in:

China
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Located in:

India
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Located in:

India

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Looking for Olmesartan API 144689-24-7?

Description:
Here you will find a list of producers, manufacturers and traders of Olmesartan. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Olmesartan 
Synonyms:
Olmesartan medoxomil , 144689-63-4  
Cas Number:
144689-24-7 
DrugBank number:
DB00275 
Unique Ingredient Identifier:
8W1IQP3U10

About Olmesartan

What makes Olmesartan unique? Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, valsartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. Overall, olmesartan's physiologic effects lead to reduced blood pressure, lower aldosterone levels, reduced cardiac activity, and increased excretion of sodium. Olmesartan also affects the renin-angiotensin aldosterone system (RAAS), which plays an important role in hemostasis and regulation of kidney, vascular, and cardiac functions.

Pharmacological blockade of RAAS via AT1 receptor blockade inhibits negative regulatory feedback within RAAS, which is a contributing factor to the pathogenesis and progression of cardiovascular disease, heart failure, and renal disease. In particular, heart failure is associated with chronic activation of RAAS, leading to inappropriate fluid retention, vasoconstriction, and ultimately a further decline in left ventricular function. ARBs have been shown to have a protective effect on the heart by improving cardiac function, reducing afterload, increasing cardiac output and preventing ventricular hypertrophy and remodelling.

You can find more info about this product by clicking on the DB ID above.

Olmesartan is a type of Angiotensin Receptor Blockers


Angiotensin Receptor Blockers (ARBs) are a vital subcategory of pharmaceutical Active Pharmaceutical Ingredients (APIs) commonly used in the treatment of hypertension and various cardiovascular conditions. ARBs work by selectively blocking the angiotensin II type 1 receptors, which are responsible for causing vasoconstriction and promoting the release of aldosterone, a hormone that regulates blood pressure and fluid balance.

These APIs are highly effective in reducing blood pressure by preventing angiotensin II from binding to its receptors, thereby dilating blood vessels and reducing peripheral resistance. By inhibiting the angiotensin II signaling pathway, ARBs help relax and widen the blood vessels, which subsequently lowers blood pressure.

Some commonly prescribed ARBs include losartan, valsartan, and candesartan. These drugs offer several advantages over other antihypertensive medications, such as a lower risk of side effects and better tolerability. ARBs are also considered beneficial for patients with certain comorbidities, including heart failure and diabetic nephropathy.

Pharmaceutical companies play a crucial role in the development and manufacturing of high-quality ARB APIs. Stringent quality control measures and adherence to regulatory guidelines ensure the safety, efficacy, and reliability of these APIs. Moreover, the market demand for ARBs is consistently growing, presenting a significant opportunity for pharmaceutical companies to cater to the increasing medical needs of patients suffering from hypertension and related cardiovascular conditions.

In conclusion, Angiotensin Receptor Blockers (ARBs) are a valuable subcategory of pharmaceutical APIs that effectively manage hypertension and cardiovascular diseases. With their ability to target the angiotensin II receptors, ARBs provide a reliable therapeutic option for patients and contribute to improving overall cardiovascular health.


Olmesartan (Angiotensin Receptor Blockers), classified under Antihypertensive agents


Antihypertensive agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat high blood pressure, also known as hypertension. These medications are designed to lower blood pressure and reduce the risk of associated cardiovascular complications.

Antihypertensive agents function by targeting various mechanisms involved in blood pressure regulation. Some common classes of antihypertensive agents include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), beta-blockers, calcium channel blockers (CCBs), and diuretics.

ACE inhibitors work by inhibiting the enzyme responsible for converting angiotensin I to angiotensin II, a hormone that constricts blood vessels. ARBs, on the other hand, block the receptors to which angiotensin II binds, thereby preventing its vasoconstrictive effects.

Beta-blockers reduce blood pressure by blocking the effects of adrenaline and noradrenaline, which are responsible for increasing heart rate and constricting blood vessels. CCBs inhibit calcium from entering the smooth muscles of blood vessels, resulting in relaxation and vasodilation. Diuretics promote the elimination of excess fluid and sodium from the body, reducing blood volume and thereby lowering blood pressure.

Antihypertensive agents are typically prescribed based on the individual patient's condition and specific needs. They can be used alone or in combination to achieve optimal blood pressure control. It is important to note that antihypertensive agents should be taken regularly as prescribed by a healthcare professional and may require periodic monitoring to ensure their effectiveness and manage any potential side effects.

In summary, antihypertensive agents play a vital role in the management of hypertension by targeting various mechanisms involved in blood pressure regulation. These medications offer significant benefits in reducing the risk of cardiovascular complications associated with high blood pressure.



Olmesartan manufacturers | traders | suppliers

We have 43 companies offering Olmesartan produced in 7 different countries.

Get in contact with the supplier of your choice:

  • Morepen Laboratories Ltd. from India, product country of origin India
  • Shandong Octagon Chemicals Limited from China, product country of origin China
  • Sinoway industrial Co.,Ltd from China, product country of origin China
  • TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
  • Otto Brandes GmbH from Germany, product country of origin Unknown
  • Glochem from India, product country of origin India
  • Dongbang FTL from South Korea, product country of origin South Korea
  • Zhuhai Rundu from China, product country of origin China
  • Unnati Pharmaceuticals Pvt Ltd from India, product country of origin India
  • Verdant Life Sciences from India, product country of origin India
  • Kolon Life Science from South Korea, product country of origin South Korea
  • Daiichi Sankyo from Japan, product country of origin Japan
  • Qilu Tianhe from China, product country of origin China
  • Teva API from Israel, product country of origin Unknown
  • Amoli Organics from India, product country of origin Unknown
  • Hikal from India, product country of origin India
  • KRKA from Slovenia, product country of origin Unknown
  • Beijing Hope from China, product country of origin China
  • Humble Healthcaare from India, product country of origin India
  • Chinoin from Hungary, product country of origin Hungary
  • Nutra Specialities from India, product country of origin India
  • Menovo from China, product country of origin China
  • Resolution Limited from China, product country of origin China
  • Vasudha Pharma Chem Ltd. from India, product country of origin India
  • Zhejiang Tianyu from China, product country of origin China
  • HEC Pharm from Germany, product country of origin China
  • Sumitomo Chemical from Japan, product country of origin Japan
  • Torrent Pharma from India, product country of origin India
  • Sintenovo from Spain, product country of origin Spain
  • Lupin from India, product country of origin Unknown
  • Unichem Labs. from India, product country of origin Unknown
  • G.C. Chemie Pharmie Ltd from India, product country of origin India
  • Huanggang Luban Pharmaceutical Co Ltd from China, product country of origin China
  • Jubilant Generics from India, product country of origin Unknown
  • Micro Labs from India, product country of origin India
  • Cipla from India, product country of origin Unknown
  • Hetero Labs from India, product country of origin India
  • Mylan from India, product country of origin India
  • Divis Labs. from India, product country of origin India
  • Granules India from India, product country of origin India
  • MSN Labs. from India, product country of origin India
  • Glenmark Pharma from India, product country of origin India
  • Moehs from Spain, product country of origin Spain

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