Fidaxomicin | compare suppliers & send inquiries for free
Apino Pharma Co., Ltd.
MOQ: 1 g
North China Pharma Group Aino
Looking for Fidaxomicin 873857-62-6?
So, what does it do? Fidaxomicin is a novel macrolide antibiotic used in the treatment of diarrhea caused by Clostridioides (formerly Clostridium) difficile in adult and pediatric patients over the age of 6 months.10 Fidaxomicin is a naturally-occurring 18-member macrocycle derived from fermentation.Because fidaxomicin contains an 18-membered lactone ring in its structure, it is referred to as a macrocyclic lactone antibiotic drug.The antibacterial activity of fidaxomicin is distinct from macrolides and rifamycins, as the bactericidal activity is time-dependent, and not concentration-dependent.
Fidaxomicin was the first macrocyclic lactone antibiotic with activity against C. difficile,4 and it displays a narrow spectrum of activity against gram-positive anaerobes. It mediates its potent bactericidal action on the bacteria by inhibiting the bacterial RNA synthase, thereby disrupting bacterial transcription. The minimum inhibitory concentration (MIC90) for fidaxomicin is four times less than that of vancomycin, which was the primary drug of choice for C. difficile infection before the approval of fidaxomicin.Unlike vancomycin, however, fidaxomicin has a negligible effect on normal colonic microflora.
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Fidaxomicin manufacturers | traders | suppliers
We have 3 companies offering Fidaxomicin from 1 different countries.
Get in contact with the supplier of your choice:
- Apino Pharma Co., Ltd. from China
- BrightGene from China
- North China Pharma Group Aino from China
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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