Gmp (Guanosine 3'-monophosphate) API Manufacturers & Suppliers
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Guanosine 3'-monophosphate | CAS No: 117-68-0 | GMP-certified suppliers
A medication that provides a purine nucleotide essential for nucleic acid research and potential biotechnological applications in RNA synthesis and intracellular signaling pathways.
Therapeutic categories
Guanine NucleotidesHeterocyclic Compounds, Fused-RingIsomerismNucleic Acids, Nucleotides, and NucleosidesNucleotidesPurine Nucleotides
Generic name
Guanosine 3'-monophosphate
Molecule type
small molecule
CAS number
117-68-0
DrugBank ID
DB03315
Approval status
Experimental drug
Product Snapshot
- Guanosine 3'-monophosphate is an oral small molecule formulation
- It is primarily investigated for potential applications in nucleic acid metabolism and related therapeutic research
- The compound currently holds an experimental status with no approved regulatory market authorization
Clinical Overview
Guanosine 3'-monophosphate (CAS number 117-68-0) is an organic compound classified within the class of ribonucleoside 3'-phosphates. These molecules are characterized by the attachment of a phosphate group to the 3' carbon of the ribose sugar moiety. In this case, guanine serves as the nucleobase, placing the compound within purine nucleotides, a subgroup of heterocyclic compounds important in nucleic acid biology.
As an individual agent, guanosine 3'-monophosphate remains primarily experimental and does not have a defined or approved clinical indication. Its pharmacodynamics and precise mechanism of action have not been characterized in clinical or preclinical settings. However, as a purine ribonucleotide, it is structurally related to endogenous nucleotides involved in critical biological processes such as RNA synthesis and intracellular signaling.
Pharmacokinetic properties including absorption, distribution, metabolism, and excretion (ADME) parameters are not established for guanosine 3'-monophosphate as a therapeutic agent. The compound is naturally occurring and participates in nucleotide metabolism pathways, but exogenous administration pharmacokinetics remain undefined.
Safety and toxicity data specific to guanosine 3'-monophosphate have not been documented in the scientific literature for pharmaceutical use. The compound is generally studied as a biochemical intermediate rather than a therapeutic agent, and thus does not have recognized toxicity profiles or clinical safety considerations.
Currently, guanosine 3'-monophosphate is recognized mainly within research contexts and applied experimentally rather than as a marketed drug substance. There are no notable branded pharmaceuticals directly associated with this compound.
For API sourcing, high purity and strict characterization of guanosine 3'-monophosphate are essential given its role in nucleic acid-related research and potential biotechnological applications. Suppliers should provide comprehensive batch-specific certificates of analysis confirming identity, purity, and absence of degradation products, compliant with relevant pharmacopeial or regulatory standards where applicable.
As an individual agent, guanosine 3'-monophosphate remains primarily experimental and does not have a defined or approved clinical indication. Its pharmacodynamics and precise mechanism of action have not been characterized in clinical or preclinical settings. However, as a purine ribonucleotide, it is structurally related to endogenous nucleotides involved in critical biological processes such as RNA synthesis and intracellular signaling.
Pharmacokinetic properties including absorption, distribution, metabolism, and excretion (ADME) parameters are not established for guanosine 3'-monophosphate as a therapeutic agent. The compound is naturally occurring and participates in nucleotide metabolism pathways, but exogenous administration pharmacokinetics remain undefined.
Safety and toxicity data specific to guanosine 3'-monophosphate have not been documented in the scientific literature for pharmaceutical use. The compound is generally studied as a biochemical intermediate rather than a therapeutic agent, and thus does not have recognized toxicity profiles or clinical safety considerations.
Currently, guanosine 3'-monophosphate is recognized mainly within research contexts and applied experimentally rather than as a marketed drug substance. There are no notable branded pharmaceuticals directly associated with this compound.
For API sourcing, high purity and strict characterization of guanosine 3'-monophosphate are essential given its role in nucleic acid-related research and potential biotechnological applications. Suppliers should provide comprehensive batch-specific certificates of analysis confirming identity, purity, and absence of degradation products, compliant with relevant pharmacopeial or regulatory standards where applicable.
Identification & chemistry
| Generic name | Guanosine 3'-monophosphate |
|---|---|
| Molecule type | Small molecule |
| CAS | 117-68-0 |
| UNII | 839SG0O89X |
| DrugBank ID | DB03315 |
Pharmacology
Targets
| Target | Organism | Actions |
|---|---|---|
| Ribonuclease | Bacillus pumilus | |
| Bifunctional protein PyrR | Bacillus caldolyticus |
Formulation & handling
- Guanosine 3'-monophosphate is a small molecule suitable for oral formulation due to its high water solubility and low logP value.
- The compound’s ribonucleoside phosphate structure suggests sensitivity to enzymatic degradation, warranting consideration of stabilizers or protective formulation strategies.
- As a solid with a relatively low molecular weight, it requires controlled moisture conditions to maintain stability during storage and handling.
