Methylnaltrexone API Manufacturers & Suppliers
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Looking for Methylnaltrexone API 916055-93-1?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Methylnaltrexone. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Methylnaltrexone
- Synonyms:
- MNTX
- Cas Number:
- 916055-93-1
- DrugBank number:
- DB06800
- Unique Ingredient Identifier:
- 0RK7M7IABE
About Methylnaltrexone
It's time for some technical information for the ones who understand chemistry: Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms. It is also a weak CYP2D6 inhibitor. FDA approved in 2008.
You can find more info about this product by clicking on the DB ID above.
Methylnaltrexone is a type of Opioid antagonists
Opioid antagonists are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) that play a vital role in the management and treatment of opioid-related disorders. These powerful substances bind to opioid receptors in the brain, blocking the effects of opioids and reversing their potentially life-threatening effects.
Opioid antagonists work by competitively binding to opioid receptors, preventing opioids from attaching to these receptors and inhibiting their activity. This mechanism of action effectively counteracts the effects of opioids, including pain relief, sedation, and respiratory depression. By blocking the receptors, opioid antagonists can rapidly reverse the effects of opioid overdose, providing a vital emergency intervention.
One of the widely used opioid antagonists is naloxone, a highly effective and fast-acting medication. Naloxone is commonly administered in emergency settings, such as hospitals and ambulances, as well as by first responders and bystanders. Its rapid onset of action and short duration make it an essential tool for reversing opioid overdoses, potentially saving lives.
Opioid antagonists not only serve as a critical intervention for overdose cases but also have applications in the management of opioid addiction. By blocking the rewarding effects of opioids, these pharmaceutical APIs can help reduce cravings and prevent relapse in individuals undergoing opioid dependence treatment.
In conclusion, opioid antagonists are indispensable pharmaceutical APIs in combating the devastating effects of opioids. Their ability to bind to opioid receptors and counteract the effects of opioids makes them essential in both emergency situations and addiction treatment. Naloxone, among other opioid antagonists, stands as a crucial tool in saving lives and addressing the opioid crisis.
Methylnaltrexone manufacturers | traders | suppliers
We have 3 companies offering Methylnaltrexone produced in 1 different countries.
Get in contact with the supplier of your choice:
- Chongqing Land Tower from China, product country of origin China
- Mallinckrodt from United States, product country of origin Unknown
- Noramco from United States, product country of origin United States
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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