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Magnesium phosphate anhydrous (Magnesium phosphate) API Manufacturers & Suppliers
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Magnesium phosphate | CAS No: 7757-87-1 | GMP-certified suppliers
A medication that supports electrolyte balance and neuromuscular function, used primarily in intravenous solutions for blood substitutes and electrolyte replenishment.
Therapeutic categories
Product Snapshot
- Magnesium phosphate is available in oral dosage forms including lozenges and tablets
- It is primarily utilized for mineral supplementation and electrolyte balance support
- The compound is currently in experimental status with no approved regulatory market authorization
Clinical Overview
Pharmacologically, magnesium phosphate functions as a source of magnesium and phosphate ions, both essential electrolytes involved in numerous physiological processes. Magnesium ions play a critical role in neuromuscular transmission, enzymatic activity, and cellular energy metabolism. Phosphate is integral to cellular signaling, bone mineralization, and acid-base balance. Though the precise mechanism of action for magnesium phosphate in therapeutic contexts remains unspecified, its administration may influence electrolyte homeostasis and neuromuscular function indirectly.
Absorption, distribution, metabolism, and excretion (ADME) characteristics are not widely documented specifically for magnesium phosphate as an API. Generally, magnesium and phosphate ions derived from such compounds exhibit bioavailability dependent on formulation, route of administration, and physiological status. Intravenous formulations may target rapid replenishment of ions, while oral forms tend toward slower absorption and release.
Safety considerations primarily relate to electrolyte balance. Excessive magnesium or phosphate intake can lead to hypermagnesemia or hyperphosphatemia, potentially resulting in neuromuscular and cardiovascular disturbances. Careful monitoring is necessary, especially in patients with renal impairment. Toxicity profiles are not extensively characterized for magnesium phosphate itself; however, known effects of magnesium and phosphate excess guide safety assessments.
Magnesium phosphate currently holds an experimental grouping and is included in drug categories such as agents producing indirect neuromuscular blockade, electrolyte solutions, and blood substitute components. Notable pharmaceutical products or brands directly referencing magnesium phosphate as a principal API are not widely documented.
From an API sourcing perspective, magnesium phosphate should comply with stringent quality standards to ensure purity, consistent particle size, and absence of contaminants. Given its inorganic nature, control of heavy metals, residual solvents, and microbial contamination is critical. Manufacturers and procurement professionals should verify certification according to pharmacopeial monographs or equivalent specifications applicable in target regulatory regions.
Identification & chemistry
| Generic name | Magnesium phosphate |
|---|---|
| Molecule type | Small molecule |
| CAS | 7757-87-1 |
| UNII | XMK14ETW2D |
| DrugBank ID | DB13862 |
Formulation & handling
- Magnesium phosphate is formulated primarily for oral administration, typically in lozenge or tablet forms.
- As an inorganic small molecule with low lipophilicity (LogP -1), it is likely stable under standard storage conditions and not sensitive to food intake.
- Handling considerations include its solid state, which facilitates formulation into solid oral dosage forms without the need for special containment measures.
Regulatory status
Magnesium phosphate is a type of Additives
Additives in the pharmaceutical API category refer to a group of chemical substances that are incorporated into pharmaceutical products to enhance their stability, functionality, or performance. These additives play a crucial role in ensuring the quality, safety, and efficacy of medications.
One common type of additive used in pharmaceuticals is preservatives. Preservatives are added to prevent microbial growth and maintain the integrity of the product throughout its shelf life. They help to safeguard against contamination and maintain the potency of the active pharmaceutical ingredient (API). Some commonly used preservatives include benzyl alcohol, phenol, and parabens.
Another important group of additives is antioxidants. Antioxidants are added to pharmaceutical formulations to prevent or delay the oxidation of APIs, which can lead to degradation and loss of potency. Examples of antioxidants commonly used in pharmaceuticals include ascorbic acid (vitamin C) and tocopherols (vitamin E).
In addition to preservatives and antioxidants, other additives like flavorings, colorants, and sweeteners may be incorporated into pharmaceutical products to improve their palatability and patient acceptability.
It is crucial to note that the use of additives in pharmaceuticals is strictly regulated by health authorities to ensure their safety and efficacy. Manufacturers must comply with stringent quality control standards and guidelines to guarantee the proper use and appropriate levels of additives in pharmaceutical products.
Overall, additives play a vital role in the pharmaceutical industry by enhancing the stability, functionality, and patient acceptability of medications. Their careful selection and incorporation contribute to the overall quality and effectiveness of pharmaceutical products.
Magnesium phosphate API manufacturers & distributors
Compare qualified Magnesium phosphate API suppliers worldwide. We currently have 1 companies offering Magnesium phosphate API, with manufacturing taking place in 1 different countries. Use the table below to review supplier type, countries of origin, certifications, product portfolio and GMP audit availability.
| Supplier | Type | Country | Product origin | Certifications | Portfolio |
|---|---|---|---|---|---|
| Acta minerals | Producer | Netherlands | Netherlands | BSE/TSE, CoA, GMP, MSDS | 67 products |
When sending a request, specify which Magnesium phosphate API quality you need: for example EP (Ph. Eur.), USP, JP, BP, or another pharmacopoeial standard, as well as the required grade (base, salt, micronised, specific purity, etc.).
Use the list above to find high-quality Magnesium phosphate API suppliers. For example, you can select GMP, FDA or ISO certified suppliers. Visit our help page to learn more about sourcing APIs via Pharmaoffer.
