Adrenocorticotropic hormones


Adrenocorticotropic hormones (ACTH) belong to the pharmaceutical API (Active Pharmaceutical Ingredient) subcategory, playing a vital role in the endocrine system. ACTH, also known as corticotropin, is a hormone synthesized and secreted by the anterior pituitary gland.

ACTH acts as a key regulator of the body's response to stress, controlling the production and release of cortisol, a hormone essential for various physiological processes. Its primary function is to stimulate the adrenal cortex to produce and secrete cortisol, which is crucial for maintaining normal metabolism, immune response, and stress adaptation.

Pharmaceutical companies produce synthetic ACTH as an API, which can be utilized for therapeutic purposes. It is commonly used in medical treatments involving adrenal insufficiency, such as Addison's disease. Synthetic ACTH helps to diagnose and manage these conditions by stimulating the adrenal glands to produce cortisol, aiding in the restoration of hormonal balance.

Moreover, ACTH is also used in diagnostic procedures to assess the functionality of the adrenal glands. By administering synthetic ACTH, healthcare professionals can evaluate the response of the adrenal glands and diagnose conditions like adrenal gland disorders or pituitary gland abnormalities.

In conclusion, ACTH is an important pharmaceutical API subcategory that encompasses synthetic corticotropin hormone. Its clinical applications include treatment of adrenal insufficiency and diagnosis of adrenal gland disorders. Pharmaceutical companies manufacture synthetic ACTH to ensure the availability of this crucial hormone for medical interventions.

NameCAS number
Desoxycorticosterone Pivalate808-48-0