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2-mercaptobenzoic acid (Thiosalicylic acid) API Manufacturers & Suppliers

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Thiosalicylic acid | CAS No: 147-93-3 | GMP-certified suppliers

A medication that serves as an experimental compound in research related to analgesic and sensory system disorders, requiring stringent quality control for pharmaceutical development.

Therapeutic categories

Acids, CarbocyclicAlkylmercury CompoundsAnalgesicsAnalgesics, Non-NarcoticBenzene DerivativesBenzoates
Generic name
Thiosalicylic acid
Molecule type
small molecule
CAS number
147-93-3
DrugBank ID
DB14026
Approval status
Experimental drug

Product Snapshot

  • Thiosalicylic acid is an oral small molecule compound
  • It is primarily investigated for potential applications in dermatological and antimicrobial therapies
  • This API is currently experimental and has not received approval from major regulatory agencies such as the FDA or EMA

Clinical Overview

Thiosalicylic acid (CAS number 147-93-3) is an organosulfur compound structurally related to salicylic acid derivatives. It belongs to multiple chemical categories, including hydroxy acids, benzoates, and sulfur compounds, which are relevant to its chemical and potentially biological properties. Despite its structural similarity to non-narcotic analgesic agents and salicylates, thiosalicylic acid remains classified as an experimental compound with no formally established clinical indications or approved therapeutic uses.

The mechanism of action for thiosalicylic acid has not been definitively characterized in the literature. As an experimental entity, pharmacodynamic profiles, including specific receptor interactions or physiological pathways, have not been concretely elucidated. This lack of data limits its application in clinical or pharmacological contexts.

Pharmacokinetic parameters such as absorption, distribution, metabolism, and excretion (ADME) have not been well documented for thiosalicylic acid. Consequently, detailed information regarding bioavailability, half-life, metabolic transformation, or elimination routes remains unavailable in authoritative sources.

Safety and toxicity profiles are likewise insufficiently described. Given its classification among organomercury and alkylmercury compound categories, which often raise concerns about systemic toxicity, careful evaluation is warranted. However, absence of systematic toxicological data precludes definitive risk assessments or established safety guidelines.

No marketed pharmaceutical products contain thiosalicylic acid as an active ingredient, and it currently lacks regulatory approvals from global health authorities. Its use remains confined to experimental research settings, including potential applications in medicinal chemistry or biochemical investigations.

Sourcing of thiosalicylic acid APIs requires strict adherence to quality control parameters, particularly with respect to purity, residual solvents, and potential heavy metal contaminants. Suppliers should provide certificates of analysis consistent with pharmacopeial standards appropriate for research-grade chemicals. Documentation of synthetic origin, batch consistency, and compliance with international regulatory frameworks is essential to ensure suitability for pharmaceutical development or investigational use.

Identification & chemistry

Generic name Thiosalicylic acid
Molecule type Small molecule
CAS 147-93-3
UNII CIP6LXN5XW
DrugBank ID DB14026

Formulation & handling

  • Thiosalicylic acid is a small molecule API available as a solid with moderate water solubility suitable for oral dosage forms. The molecular weight and logP indicate balanced lipophilicity, which may influence formulation strategies for absorption. Handling should consider standard precautions for solid small molecules without special stability or sensitivity issues reported.

Regulatory status

Thiosalicylic acid is a type of Analgesics


Analgesics are a category of pharmaceutical Active Pharmaceutical Ingredients (APIs) that are commonly used to relieve pain. They are designed to alleviate discomfort by targeting the body's pain receptors or by reducing inflammation. Analgesics are widely utilized in the medical field to manage various types of pain, ranging from mild to severe.

One of the primary classes of analgesics is nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs work by inhibiting the production of prostaglandins, substances that contribute to pain and inflammation. This class includes well-known drugs like ibuprofen and naproxen. Another class of analgesics is opioids, which are derived from opium or synthetic compounds that mimic the effects of opium. Opioids act on the central nervous system to reduce pain perception and provide potent pain relief. Examples of opioids include morphine, codeine, and oxycodone.

Analgesics are available in various forms, such as tablets, capsules, creams, and injections, allowing for different routes of administration based on the patient's needs. They are commonly used to manage pain associated with conditions like arthritis, headaches, dental procedures, and post-operative recovery.

It is important to note that analgesics should be used under medical supervision, as improper use or overuse can lead to adverse effects, including gastrointestinal complications, addiction, and respiratory depression in the case of opioids. Therefore, it is crucial for healthcare professionals to assess each patient's individual needs and prescribe the appropriate analgesic and dosage.

In summary, analgesics are a vital category of pharmaceutical APIs used to alleviate pain by targeting pain receptors or reducing inflammation. With various classes and forms available, they provide valuable options for pain management when used responsibly and under medical guidance.