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Elvucitabine
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Looking for Elvucitabine API 181785-84-2?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Elvucitabine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Elvucitabine
- Synonyms:
- B-L-Fd4C , Elvucitabine
- Cas Number:
- 181785-84-2
- DrugBank number:
- DB06236
- Unique Ingredient Identifier:
- M09BUF90C0
General Description:
Elvucitabine is a chemical compound identified by the CAS number 181785-84-2. It is known for its distinct pharmacological properties and applications.
Indications:
This drug is primarily indicated for: Investigated for use/treatment in hepatitis (viral, B) and HIV infection. Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Mechanism of Action:
Elvucitabine functions by: Elvucitabine is a L-cytosine Nucleoside analog Reverse Transcriptase Inhibitor (NRTIs) anti-HIV drug. NRTI's inhibit the activity of viral RNA-directed DNA polymerase (i.e, reverse transcriptase). It is believed that inhibition of reverse transcriptase interferes with the generation of DNA copies of viral RNA, which, in turn, are necessary for synthesis of new virions. Intracellular enzymes subsequently eliminate the HIV particle that previously had been uncoated, and left unprotected, during entry into the host cell. Thus, reverse transcriptase inhibitors are virustatic and do not eliminate HIV from the body. This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Classification:
Elvucitabine belongs to the class of organic compounds known as nucleoside and nucleotide analogues. These are analogues of nucleosides and nucleotides. These include phosphonated nucleosides, C-glycosylated nucleoside bases, analogues where the sugar unit is a pyranose, and carbocyclic nucleosides, among others, classified under the direct parent group Nucleoside and nucleotide analogues. This compound is a part of the Organic compounds, falling under the Nucleosides, nucleotides, and analogues superclass, and categorized within the Nucleoside and nucleotide analogues class, specifically within the None subclass.
Categories:
Elvucitabine is categorized under the following therapeutic classes: Anti-HIV Agents, Anti-Infective Agents, Anti-Retroviral Agents, Antiviral Agents, Deoxycytidine, Deoxyribonucleosides, Dideoxynucleosides, Enzyme Inhibitors, HIV Reverse Transcriptase, Nucleic Acid Synthesis Inhibitors, Nucleic Acids, Nucleotides, and Nucleosides, Nucleoside Reverse Transcriptase Inhibitors, Nucleosides, Pyrimidine Nucleosides, Pyrimidines, Reverse Transcriptase Inhibitors. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Elvucitabine is a type of Anti-HIV
The Anti-HIV category of pharmaceutical APIs comprises a range of active pharmaceutical ingredients (APIs) specifically designed to combat the human immunodeficiency virus (HIV). These APIs play a critical role in the development and production of antiretroviral drugs, which are used to treat HIV infections and prevent the progression to acquired immunodeficiency syndrome (AIDS).
Anti-HIV APIs work by targeting various stages of the HIV life cycle, inhibiting viral replication and reducing the viral load in the body. Some commonly used APIs in this category include nucleoside reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), protease inhibitors (PIs), and integrase inhibitors (INIs).
NRTIs, such as tenofovir and emtricitabine, act by blocking the reverse transcriptase enzyme, an essential component in the replication of the virus. NNRTIs, such as efavirenz and nevirapine, bind to the reverse transcriptase enzyme, preventing its proper functioning. PIs, like ritonavir and atazanavir, inhibit the protease enzyme, crucial for viral maturation and assembly. INIs, such as raltegravir and dolutegravir, target the integrase enzyme, impeding viral integration into the host's DNA.
These APIs are carefully synthesized and undergo rigorous quality testing to ensure their safety, efficacy, and compliance with regulatory standards. Pharmaceutical companies utilize these APIs as key building blocks to formulate antiretroviral medications, which are then prescribed to individuals living with HIV/AIDS worldwide.
Overall, the Anti-HIV API category plays a vital role in the ongoing battle against HIV/AIDS, offering effective treatment options and improved quality of life for patients affected by this challenging condition.
