Ditiocarb zinc API Manufacturers & Suppliers
0 verified results
All Ditiocarb zinc data. Full access. Full negotiation power
Commercial-scale Suppliers
Join our notification list by following this page.
Click the button below to find out more
Click the button below to switch over to the contract services area of Pharmaoffer.
Total market transparency
Supplier trade data access
Buyer / supplier flow comparison
Ditiocarb zinc | CAS No: 14324-55-1 | GMP-certified suppliers
A medication that aids in diagnosing allergic contact dermatitis through standardized epicutaneous patch testing for individuals aged six years and older.
Therapeutic categories
Primary indications
- Ditiocarb Zinc is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older
Product Snapshot
- Ditiocarb zinc is formulated as a cutaneous epicutaneous patch test kit
- It is used primarily for the diagnostic evaluation of allergic contact dermatitis
- The product is approved for use in the US market
Clinical Overview
The clinical application of ditiocarb zinc involves its use as a standardized chemical allergen. When applied via patch testing, it serves as an aid in identifying patients sensitized to this compound, contributing to the diagnosis and management of ACD. Sensitivity to ditiocarb zinc manifests as a dermatological allergic reaction produced by a cell-mediated immune response. Such sensitization can be confirmed through controlled patch testing under clinical supervision.
While specific pharmacodynamics and detailed mechanisms of action remain unspecified, the compound’s role as a chelating agent underlies its ability to bind divalent metal cations, including zinc and copper. This chelation capacity is pertinent to its allergenic properties, as well as its categorization among immunologic agents and chelating compounds.
Absorption, distribution, metabolism, and excretion (ADME) profiles for ditiocarb zinc are not well characterized in the literature, largely due to its primary use as a diagnostic allergen applied topically rather than systemically.
Safety and toxicity considerations include its known potential as a dermatological sensitizer and allergen. Clinical patch testing is essential to establish hypersensitivity, which may guide avoidance and management strategies. Due to its sensitizing properties, handling in manufacturing and clinical settings requires appropriate safety measures to minimize unintended exposure.
Ditiocarb zinc is classified among a range of pharmacologic and investigational categories including carbamates, immunologic factors, and sulfur compounds. Notable usage is confined to dermatological diagnostic contexts rather than therapeutic applications.
For pharmaceutical API procurement, focus should be placed on sourcing ditiocarb zinc that meets comprehensive purity and characterization standards to ensure reproducibility in allergenicity testing. Batch-to-batch consistency and adherence to regulatory chemical allergen guidelines are critical for reliable diagnostic performance.
Identification & chemistry
| Generic name | Ditiocarb zinc |
|---|---|
| Molecule type | Small molecule |
| CAS | 14324-55-1 |
| UNII | ICW4708Z8G |
| DrugBank ID | DB14193 |
Formulation & handling
- Ditiocarb zinc is a small molecule organosulfur compound intended for cutaneous application, not oral or injectable use.
- Its low water solubility suggests formulation may require solubilizing agents or appropriate solvent systems for effective delivery.
- The compound’s stability profile should consider potential oxidation of sulfur moieties during handling and storage.
Regulatory status
| Lifecycle | The active pharmaceutical ingredient (API) is currently marketed in the US and is approaching patent expiry, indicating a transition toward increased generic competition and market maturity. |
|---|
| Markets | US |
|---|
Supply Chain
| Supply chain summary | The manufacturing landscape for Ditiocarb zinc includes originator companies supplying branded products primarily in the US market. The presence of branded products such as the T.R.U.E. Test Thin-Layer Rapid Use Patch Test indicates established market availability, with no current indication of patent expiry, suggesting limited generic competition at this time. |
|---|
Ditiocarb zinc is a type of Antidotes, Deterrents, and Toxicologic Agents
Antidotes, Deterrents, and Toxicologic Agents are an important category of pharmaceutical Active Pharmaceutical Ingredients (APIs) that play a critical role in healthcare and toxicology. These substances are designed to counteract the effects of poisons, toxins, and overdoses, thereby saving lives and preventing severe health consequences.
Antidotes are substances that neutralize the toxic effects of certain drugs, chemicals, or poisons. They work by either directly binding to the toxic substance or by blocking its harmful actions on the body. Antidotes are administered in emergency situations to quickly reverse the effects of poisoning and restore normal physiological functions.
Deterrents, on the other hand, are pharmaceutical agents used to discourage or prevent harmful behaviors, such as substance abuse. They are designed to make the ingestion or misuse of certain substances unpleasant or less desirable. Deterrents can be formulated to cause unpleasant side effects, such as nausea or vomiting, when a particular substance is consumed in excessive amounts.
Toxicologic agents encompass a broad range of pharmaceutical APIs used in toxicology studies and research. These substances are employed to investigate the toxicity, metabolism, and mechanisms of action of various chemicals and compounds. Toxicologic agents are vital for understanding the potential hazards and risks associated with certain substances, ensuring the safety of drugs, and developing effective treatments for poisoning cases.
In conclusion, Antidotes, Deterrents, and Toxicologic Agents are essential categories of pharmaceutical APIs that address poisoning emergencies, deter harmful behaviors, and enable toxicological research. Their development and availability are crucial for safeguarding public health, enhancing patient care, and advancing our understanding of toxicology.
