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Nalorphine
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Looking for Nalorphine API 62-67-9?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Nalorphine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Nalorphine
- Synonyms:
- Nalorfina , Nalorphinum
- Cas Number:
- 62-67-9
- DrugBank number:
- DB11490
- Unique Ingredient Identifier:
- U59WB2WRY2
General Description:
Nalorphine, identified by CAS number 62-67-9, is a notable compound with significant therapeutic applications. Nalorphine is a mixed opioid agonist–antagonist. It acts at two opioid receptors—at the mu receptor it has antagonistic effects, and at the kappa receptors it exerts high-efficacy agonistic characteristics. It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.
Indications:
This drug is primarily indicated for: Used to reverse opioid overdose. Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Classification:
Nalorphine belongs to the class of organic compounds known as morphinans. These are polycyclic compounds with a four-ring skeleton with three condensed six-member rings forming a partially hydrogenated phenanthrene moiety, one of which is aromatic while the two others are alicyclic, classified under the direct parent group Morphinans. This compound is a part of the Organic compounds, falling under the Alkaloids and derivatives superclass, and categorized within the Morphinans class, specifically within the None subclass.
Categories:
Nalorphine is categorized under the following therapeutic classes: Alkaloids, Antidotes, Central Nervous System Agents, Heterocyclic Compounds, Fused-Ring, Morphinans, Opiate Alkaloids, Opioid Antagonists, Peripheral Nervous System Agents, Phenanthrenes, Semi-synthetic Opioids, Sensory System Agents. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Nalorphine is a type of Antidotes, Deterrents, and Toxicologic Agents
Antidotes, Deterrents, and Toxicologic Agents are an important category of pharmaceutical Active Pharmaceutical Ingredients (APIs) that play a critical role in healthcare and toxicology. These substances are designed to counteract the effects of poisons, toxins, and overdoses, thereby saving lives and preventing severe health consequences.
Antidotes are substances that neutralize the toxic effects of certain drugs, chemicals, or poisons. They work by either directly binding to the toxic substance or by blocking its harmful actions on the body. Antidotes are administered in emergency situations to quickly reverse the effects of poisoning and restore normal physiological functions.
Deterrents, on the other hand, are pharmaceutical agents used to discourage or prevent harmful behaviors, such as substance abuse. They are designed to make the ingestion or misuse of certain substances unpleasant or less desirable. Deterrents can be formulated to cause unpleasant side effects, such as nausea or vomiting, when a particular substance is consumed in excessive amounts.
Toxicologic agents encompass a broad range of pharmaceutical APIs used in toxicology studies and research. These substances are employed to investigate the toxicity, metabolism, and mechanisms of action of various chemicals and compounds. Toxicologic agents are vital for understanding the potential hazards and risks associated with certain substances, ensuring the safety of drugs, and developing effective treatments for poisoning cases.
In conclusion, Antidotes, Deterrents, and Toxicologic Agents are essential categories of pharmaceutical APIs that address poisoning emergencies, deter harmful behaviors, and enable toxicological research. Their development and availability are crucial for safeguarding public health, enhancing patient care, and advancing our understanding of toxicology.
