Valerian API Manufacturers

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Looking for Valerian API 8057-49-6?

Description:
Here you will find a list of producers, manufacturers and distributors of Valerian. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Valerian 
Synonyms:
Valerianae radix  
Cas Number:
8057-49-6 
DrugBank number:
DB13196 
Unique Ingredient Identifier:
JWF5YAW3QW

General Description:

Valerian, identified by CAS number 8057-49-6, is a notable compound with significant therapeutic applications. Valerian is extracted from a herb that is a perennial flowering plant. Valerian root is reported to have sedative and anxiolytic effects however its mechanism of action is not completely understood. Valerian has been used in the treatment of conditions including sleep disorders, anxiety, attention deficit-hyperactivity disorder (ADHD) and joint pain. is a derivative of valeric acid, which is obtained from the plant root. Valerian is a food ingredient permitted for direct addition to food for human consumption as a natural flavoring substance.

Categories:

Valerian is categorized under the following therapeutic classes: Angiosperms, Biological Products, Central Nervous System Depressants, Complex Mixtures, Dipsacales, Embryophyta, Eukaryota, Herbs and Natural Products, Hypnotics and Sedatives, Miscellaneous Anxiolytics Sedatives and Hypnotics, Nervous System, Pharmaceutical Preparations, Plant Preparations, Psycholeptics, Streptophyta, Tracheophyta, Valerianaceae, Viridiplantae. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.

Valerian is a type of Barbiturates


Barbiturates are a category of pharmaceutical active pharmaceutical ingredients (APIs) that have sedative, hypnotic, and anticonvulsant properties. They belong to the class of drugs called depressants, which slow down the central nervous system (CNS) activity. Barbiturates have been widely used in the medical field for their ability to induce sleep, reduce anxiety, and control seizures.

The mechanism of action of barbiturates involves enhancing the effects of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) in the brain. GABA inhibits the transmission of signals between nerve cells, leading to relaxation and sedation. Barbiturates bind to specific GABA receptors, increasing the inhibitory effects of GABA and resulting in a calming effect on the CNS.

In the past, barbiturates were commonly prescribed for insomnia, anxiety disorders, and epilepsy. However, their use has decreased significantly due to the emergence of safer and more effective alternatives with fewer side effects. Nonetheless, barbiturates are still utilized in certain medical situations, such as anesthesia induction, emergency seizure control, and in some cases of refractory epilepsy.

Despite their therapeutic benefits, barbiturates carry potential risks and side effects. They can cause drowsiness, impaired coordination, and dependence when used for extended periods. Overdose of barbiturates can be life-threatening, leading to respiratory depression and coma.

In conclusion, barbiturates are a class of API widely known for their sedative, hypnotic, and anticonvulsant properties. While their use has diminished over time, they remain important in specific medical contexts. Proper caution and medical supervision are crucial when using barbiturates to ensure safety and efficacy.