Pimecrolimus API Manufacturers

Looking for Pimecrolimus API 137071-32-0?

Description:

Here you will find a list of producers, manufacturers and distributors of Pimecrolimus. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.

API | Excipient name:

Pimecrolimus 

Synonyms:

Pimecrolimus , Pimecrolimusum  

Cas Number:

137071-32-0 

DrugBank number:

DB00337 

Unique Ingredient Identifier:

7KYV510875

Pimecrolimus is a type of Calcineurin inhibitors

Calcineurin inhibitors are a vital subcategory of pharmaceutical Active Pharmaceutical Ingredients (APIs) widely used in the treatment of various medical conditions. These inhibitors work by suppressing the activity of calcineurin, an enzyme that plays a crucial role in the immune response.

The primary application of calcineurin inhibitors is in the field of immunosuppression, particularly in organ transplantation. These medications prevent the rejection of transplanted organs by inhibiting the production of cytokines, such as interleukin-2, which are responsible for triggering the immune response. By modulating the immune system, calcineurin inhibitors enable successful transplantation and enhance patient outcomes.

Furthermore, calcineurin inhibitors find utility in the treatment of autoimmune disorders, including psoriasis and rheumatoid arthritis. These medications help alleviate symptoms and reduce inflammation by interfering with the immune system's response.

The two most commonly used calcineurin inhibitors are cyclosporine and tacrolimus. These compounds exhibit high specificity and affinity for calcineurin, ensuring effective immunosuppression. Both drugs are available in various formulations, including oral capsules, injectables, and topical preparations, enabling healthcare professionals to tailor treatment to individual patient needs.

It is important to note that calcineurin inhibitors may have certain side effects, including nephrotoxicity, hypertension, and increased susceptibility to infections. Close monitoring of patients and appropriate dosage adjustments are crucial to maintaining the delicate balance between immune suppression and overall health.

In summary, calcineurin inhibitors represent a vital subcategory of pharmaceutical APIs used in immunosuppressive therapy for organ transplantation and autoimmune disorders. Their ability to modulate the immune response plays a crucial role in achieving successful patient outcomes.

Pimecrolimus (Calcineurin inhibitors), classified under Dermatological Agents

Dermatological agents are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used in the formulation of various skincare and dermatology products. These APIs are specifically designed to target and treat skin conditions, offering effective solutions for a wide range of dermatological concerns.

Dermatological agents encompass a diverse array of compounds, including corticosteroids, antifungal agents, antibacterials, retinoids, and immunomodulators. Each API within this category possesses unique properties and mechanisms of action, enabling them to address specific skin-related issues.

Corticosteroids, for instance, are potent anti-inflammatory agents commonly used in the treatment of skin conditions like eczema, psoriasis, and dermatitis. Antifungal agents, on the other hand, combat fungal infections such as athlete's foot or ringworm. Antibacterials are effective against bacterial infections, while retinoids promote skin cell turnover and treat acne and photoaging. Immunomodulators regulate the immune response, providing relief from conditions like atopic dermatitis.

The development and application of dermatological APIs involve rigorous research, clinical trials, and regulatory compliance. These APIs are typically integrated into topical creams, ointments, gels, and lotions, ensuring targeted delivery to the affected areas of the skin.

Dermatological agents play a crucial role in the management and treatment of various skin disorders. By harnessing the therapeutic properties of these APIs, pharmaceutical companies can develop innovative skincare products that cater to the diverse needs of individuals seeking effective dermatological solutions.

• Changzhou Comwin Fine Chemicals Co., Ltd from China, product country of origin China
• Shandong Octagon Chemicals Limited from China, product country of origin China
• BrightGene from China, product country of origin China
• Euticals from Italy, product country of origin Unknown
• Biocon from India, product country of origin India
• Lek Pharma from Slovenia, product country of origin Slovenia

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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