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D-chiro-Inositol API Manufacturers & Suppliers

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Commercial-scale Suppliers

Distributor
Produced in  China
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Employees: 50+

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Audit Report: Currently Eurofins has no report for this supplier. Contact them to let them know you're interested!
Certifications: CoA

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D-chiro-Inositol | CAS No: 643-12-9 | GMP-certified suppliers

A medication that is under investigation for potential benefits in managing polycystic ovary syndrome and related metabolic and endocrine disorders.

Generic name
D-chiro-Inositol
Molecule type
small molecule
CAS number
643-12-9
DrugBank ID
DB15350
Approval status
Investigational drug

Product Snapshot

  • D-chiro-Inositol is an oral small molecule formulation
  • It is primarily investigated for metabolic and endocrinological applications
  • The compound is currently in investigational status without approved regulatory market authorization

Clinical Overview

D-chiro-Inositol (CAS Number 643-12-9) is a stereoisomer of inositol that is currently under clinical investigation, notably in the context of polycystic ovary syndrome (PCOS). It is being studied as part of a combined formulation with myo-inositol at a specific ratio (3.6:1) to evaluate potential therapeutic benefits in women diagnosed with PCOS, as registered in clinical trial NCT03201601.

The clinical indication for D-chiro-Inositol has not been formally established, and its pharmacodynamics and mechanism of action remain to be fully elucidated. It is classified as an investigational substance, and no regulatory approvals have been granted for therapeutic use at this time.

From a pharmacological perspective, inositol stereoisomers like D-chiro-Inositol are implicated in various intracellular signaling pathways, including insulin signal transduction, which may underlie their potential utility in metabolic and endocrine disorders. However, specific mechanisms by which D-chiro-Inositol exerts biological effects are yet to be comprehensively characterized.

Key absorption, distribution, metabolism, and excretion (ADME) parameters for D-chiro-Inositol have not been widely reported, limiting detailed understanding of its pharmacokinetic profile. Likewise, safety and toxicity data remain preliminary, and no definitive safety conclusions can be drawn at this stage. Any use should be confined to well-monitored clinical research settings.

Currently, there are no notable brand names associated with D-chiro-Inositol as a pharmaceutical entity, reflecting its investigational status.

For API procurement, stringent quality control is imperative due to the investigational nature of D-chiro-Inositol. Sourcing should ensure compliance with relevant pharmacopeial standards where applicable, verification of stereoisomeric purity, and adherence to good manufacturing practices (GMP) to support clinical and regulatory requirements.

Identification & chemistry

Generic name D-chiro-Inositol
Molecule type Small molecule
CAS 643-12-9
UNII 6R79WV4R10
DrugBank ID DB15350

Formulation & handling

  • D-chiro-Inositol is a small molecule with high water solubility, suitable for oral formulations.
  • Its low LogP value indicates low lipophilicity, suggesting limited membrane permeability which may affect bioavailability.
  • Stability handling is generally straightforward due to the compound's small molecule nature and investigational status requires close monitoring of formulation performance.

Regulatory status

D-chiro-Inositol API manufacturers & distributors

Compare qualified D-chiro-Inositol API suppliers worldwide. We currently have 1 companies offering D-chiro-Inositol API, with manufacturing taking place in 1 different countries. Use the table below to review supplier type, countries of origin, certifications, product portfolio and GMP audit availability.

SupplierTypeCountryProduct originCertificationsPortfolio
Distributor
China China CoA757 products

When sending a request, specify which D-chiro-Inositol API quality you need: for example EP (Ph. Eur.), USP, JP, BP, or another pharmacopoeial standard, as well as the required grade (base, salt, micronised, specific purity, etc.).

Use the list above to find high-quality D-chiro-Inositol API suppliers. For example, you can select GMP, FDA or ISO certified suppliers. Visit our help page to learn more about sourcing APIs via Pharmaoffer.