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Dodecyldimethylamine N-oxide | CAS No: 1643-20-5 | GMP-certified suppliers
A medication that serves as a surface-active agent for industrial and household cleaning applications, facilitating emulsification and solubilization of hydrophobic substances.
Therapeutic categories
AminesCompounds used in a research, industrial, or household settingDetergentsHousehold ProductsMethylaminesSurface-Active Agents
Generic name
Dodecyldimethylamine N-oxide
Molecule type
small molecule
CAS number
1643-20-5
DrugBank ID
DB04147
Approval status
Experimental drug
Product Snapshot
- Dodecyldimethylamine N-oxide is an excipient used in pharmaceutical formulations, typically as a surfactant
- Its primary application is in improving drug solubility and stability across various delivery platforms
- The compound is currently in an experimental status with no FDA or EMA marketing approvals
Clinical Overview
Dodecyldimethylamine N-oxide is a long-chain alkyl amine oxide characterized by a dodecyl (C12) alkyl group attached to a dimethylamine oxide moiety. It belongs to the chemical class of aminoxides, compounds distinguished by an alkyl chain ranging from C10 to C24 bonded to the amine oxide functional group. This compound is primarily utilized in research, industrial applications, and household products rather than for therapeutic purposes.
No clinical indications have been established for dodecyldimethylamine N-oxide, and it is currently classified as an experimental compound without regulatory approval for medical use. Its pharmacodynamics and mechanism of action have not been defined within a pharmacological context, as it is principally employed for its surface-active properties.
As a surface-active agent and detergent, dodecyldimethylamine N-oxide exhibits amphiphilic characteristics that facilitate the disruption of lipid bilayers and the solubilization of hydrophobic substances. This behavior lends itself to applications in cleaning formulations, where it functions to emulsify oils and improve the wetting properties of aqueous solutions.
Key absorption, distribution, metabolism, and excretion (ADME) parameters have not been systematically characterized, given the compound’s non-pharmaceutical classification. Safety and toxicity profiles should be evaluated with caution; like many surfactants, it may cause irritation upon contact with skin, eyes, or mucous membranes, and appropriate handling protocols should be followed in industrial or laboratory settings.
Notable brand names are not established, as the compound is predominantly supplied as a chemical reagent or raw material for formulation purposes. Its use is widespread in detergent products and household cleaners rather than therapeutic preparations.
In the context of active pharmaceutical ingredient procurement, sourcing of dodecyldimethylamine N-oxide requires verification of chemical purity, absence of contaminants, and compliance with applicable industrial standards. Certificate of analysis documentation and adherence to good manufacturing practices should be confirmed when the compound is used in formulations that demand precise quality attributes.
No clinical indications have been established for dodecyldimethylamine N-oxide, and it is currently classified as an experimental compound without regulatory approval for medical use. Its pharmacodynamics and mechanism of action have not been defined within a pharmacological context, as it is principally employed for its surface-active properties.
As a surface-active agent and detergent, dodecyldimethylamine N-oxide exhibits amphiphilic characteristics that facilitate the disruption of lipid bilayers and the solubilization of hydrophobic substances. This behavior lends itself to applications in cleaning formulations, where it functions to emulsify oils and improve the wetting properties of aqueous solutions.
Key absorption, distribution, metabolism, and excretion (ADME) parameters have not been systematically characterized, given the compound’s non-pharmaceutical classification. Safety and toxicity profiles should be evaluated with caution; like many surfactants, it may cause irritation upon contact with skin, eyes, or mucous membranes, and appropriate handling protocols should be followed in industrial or laboratory settings.
Notable brand names are not established, as the compound is predominantly supplied as a chemical reagent or raw material for formulation purposes. Its use is widespread in detergent products and household cleaners rather than therapeutic preparations.
In the context of active pharmaceutical ingredient procurement, sourcing of dodecyldimethylamine N-oxide requires verification of chemical purity, absence of contaminants, and compliance with applicable industrial standards. Certificate of analysis documentation and adherence to good manufacturing practices should be confirmed when the compound is used in formulations that demand precise quality attributes.
Identification & chemistry
| Generic name | Dodecyldimethylamine N-oxide |
|---|---|
| Molecule type | Small molecule |
| CAS | 1643-20-5 |
| UNII | 4F6FC4MI8W |
| DrugBank ID | DB04147 |
Pharmacology
Targets
| Target | Organism | Actions |
|---|---|---|
| Reaction center protein L chain | Rhodobacter sphaeroides | |
| Reaction center protein M chain | Rhodobacter sphaeroides | |
| Reaction center protein H chain | Rhodobacter sphaeroides |
Formulation & handling
- Dodecyldimethylamine N-oxide is a small molecule with limited water solubility, indicating potential formulation challenges for aqueous preparations.
- Its long-chain alkyl amine oxide structure suggests utility as a surfactant or permeation enhancer, requiring consideration in excipient compatibility.
- Solid-state handling should ensure moisture protection to maintain stability during storage and formulation processes.
