Find, compare & contact
Apoptone
API Manufacturers & Suppliers
Join our notification list by following this page.
Click the button below to find out more
Click the button below to switch over to the contract services area of Pharmaoffer.
Looking for Apoptone API 183387-50-0?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Apoptone. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Apoptone
- Synonyms:
- Cas Number:
- 183387-50-0
- DrugBank number:
- DB06307
- Unique Ingredient Identifier:
- 891O182ZP5
General Description:
Apoptone is a chemical compound identified by the CAS number 183387-50-0. It is known for its distinct pharmacological properties and applications.
Indications:
This drug is primarily indicated for: Investigated for use/treatment in cancer/tumors (unspecified). Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Mechanism of Action:
Apoptone functions by: HE3235 is a second generation antitumor agent that causes apoptosis (cell death). HE3235 inhibits the BCL2 gene which translates proteins that prevent apoptosis and stimulates the expression proteins that induce apoptosis. HE3235 also downregulates the gene that codes for the multi-drug resistant protein ABCG2 (BCRP1 – Breast Cancer Resistance Protein1). This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Classification:
Apoptone belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans, classified under the direct parent group Androgens and derivatives. This compound is a part of the Organic compounds, falling under the Lipids and lipid-like molecules superclass, and categorized within the Steroids and steroid derivatives class, specifically within the Androstane steroids subclass.
Categories:
Apoptone is categorized under the following therapeutic classes: Androstanes, Fused-Ring Compounds, Steroids. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Apoptone is a type of Hormones
Hormones are a vital category of pharmaceutical Active Pharmaceutical Ingredients (APIs) that play a crucial role in regulating various physiological processes in the human body. These chemical messengers are produced by endocrine glands and are responsible for maintaining homeostasis, growth, metabolism, and reproductive functions.
Pharmaceutical hormones are synthetic or naturally derived compounds that mimic the structure and function of endogenous hormones. They are widely used in the treatment of hormonal disorders, such as hypothyroidism, diabetes, and hormonal imbalances.
Common examples of hormone APIs include insulin, thyroid hormones (such as levothyroxine), glucocorticoids (such as prednisone), and sex hormones (such as estrogen and testosterone). These APIs are carefully synthesized, purified, and formulated to ensure optimal efficacy, stability, and bioavailability.
Hormone APIs are typically produced through advanced chemical synthesis or biotechnological processes, involving the use of genetically engineered microorganisms or mammalian cell cultures. Stringent quality control measures and regulatory guidelines ensure the purity, potency, and safety of hormone APIs.
Pharmaceutical companies and research institutions invest significant resources in developing hormone APIs, as they are fundamental for the treatment of various endocrine disorders. The demand for hormone APIs continues to grow, driven by the rising prevalence of hormonal diseases and an aging population.
In conclusion, hormone APIs are essential components of pharmaceuticals that help restore hormonal balance and alleviate various endocrine disorders. Their significance in healthcare makes them a crucial category in the pharmaceutical industry.
