Melatonin API Manufacturers

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TOP RANKING

Located in:

China

Produced in:

China

Established in: 1987

MOQ: 1 kg

Employees: 50+

ISO 9001:2015 & SGS audited supplier

One-stop CDMO Solutions for APl and Key intermediates

Specialized in APIs & Pharmaceutical Intermediates for 37 years

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • ISO9001

  • MSDS

  • GMP

  • DMF

HIGHLIGHTED

Located in:

China

Produced in:

China

Established in: 2005

MOQ: 1 kg

Employees: 85

Strict quality control

15 years of experience in API production

Provide OEM & ODM service

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • MSDS

  • ISO9001

HIGHLIGHTED

Located in:

United States

Distributor

Produced in:

World

Established in: 2005

MOQ: -

Employees: 200+

Portfolio of over 2,000 APIs

Precise quality control

End-to-end global regulatory support

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CEP

  • GMP

  • CoA

  • MSDS

  • BSE/TSE

HIGHLIGHTED

Located in:

China

Produced in:

China

Established in: 2011

MOQ: 1 kg

Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • BSE/TSE

  • MSDS

  • ISO9001

Located in:

China

Produced in:

China

Established in: 2019

MOQ: -

Employees: 50+

ISO 9001, SGS, Certificated supplier.

Audit available either on site or remote.

Professional One Stop Service for delivery to customers.

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CEP

  • WC

  • GMP

  • CoA

  • FDA

  • ISO9001

  • MSDS

  • BSE/TSE

Producer

Produced in:

India

Established in: 2021

MOQ: -

Employees: 19

API, Intermediates, Building Blocks, Impurities, Amino acids and Peptides

Small quantity APIs to commercial scale

GMP and USFDA certification based on quantity, order, assignment.

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • CoA

  • FDA

Produced in:

Unknown

Established in: 1886

MOQ: -

Employees: 275+

Raw materials, CMO and OTC products

Two GMP certified locations

Customisable (small-sized) packages

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • CoA

  • ISO9001

  • MSDS

  • BSE/TSE

Produced in:

India

Established in: 1968

MOQ: 500 g

Employees: 50+

Warehouse stock of nearly all APIs

GMP, GDP and ISO certified

Customisable (small-sized) packages

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • MSDS

  • WC

  • WHO-GMP

  • CoA

  • BSE/TSE

  • GMP

  • ISO9001

Located in:

Italy

Producer

Produced in:

Italy

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • DMF

  • CoA

Contact supplier

Replies slower than most

Located in:

Germany

Distributor

Produced in:

Unknown

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • coa

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Looking for Melatonin API 73-31-4?

Description:
Here you will find a list of producers, manufacturers and distributors of Melatonin. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Melatonin 
Synonyms:
Melatonin , Melatonine , Melatoninum  
Cas Number:
73-31-4 
DrugBank number:
DB01065 
Unique Ingredient Identifier:
JL5DK93RCL

About Melatonin

More information about this product: Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the pineal gland.

The pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone (hence the name), that is located in the center of the brain (rostro-dorsal to the superior colliculus) but outside the blood-brain barrier. The secretion of melatonin increases in darkness and decreases during exposure to light, thereby regulating the circadian rhythms of several biological functions, including the sleep-wake cycle. In particular, melatonin regulates the sleep-wake cycle by chemically causing drowsiness and lowering the body temperature. Melatonin is also implicated in the regulation of mood, learning and memory, immune activity, dreaming, fertility and reproduction. Melatonin is also an effective antioxidant. Most of the actions of melatonin are mediated through the binding and activation of melatonin receptors. Individuals with autism spectrum disorders (ASD) may have lower than normal levels of melatonin. A 2008 study found that unaffected parents of individuals with ASD also have lower melatonin levels, and that the deficits were associated with low activity of the ASMT gene, which encodes the last enzyme of melatonin synthesis. Reduced melatonin production has also been proposed as a likely factor in the significantly higher cancer rates in night workers.

Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements.

Melatonin is a type of Melatonin agonists


Melatonin agonists are a class of pharmaceutical active pharmaceutical ingredients (APIs) that interact with melatonin receptors in the body. Melatonin is a hormone naturally produced by the pineal gland in the brain and is involved in regulating the sleep-wake cycle.

Melatonin agonists mimic the effects of melatonin by binding to melatonin receptors in the brain. By activating these receptors, they help regulate circadian rhythms and promote sleep. These APIs are commonly used in the treatment of sleep disorders, such as insomnia and jet lag.

One widely used melatonin agonist is ramelteon, which selectively binds to melatonin receptors MT1 and MT2. It has a high affinity for these receptors, making it effective in promoting sleep without causing significant side effects.

Melatonin agonists offer several advantages over traditional sleep medications. They have a favorable safety profile, with minimal risk of dependence or abuse. Unlike sedative-hypnotic drugs, melatonin agonists do not suppress natural sleep architecture and are less likely to cause daytime drowsiness.

In addition to their sleep-promoting properties, melatonin agonists have shown potential in the treatment of other conditions. Research suggests they may be beneficial in managing circadian rhythm disorders, such as shift work disorder and delayed sleep phase syndrome.

Overall, melatonin agonists are a promising class of pharmaceutical APIs for improving sleep quality and addressing sleep-related disorders. Their unique mechanism of action and favorable safety profile make them a valuable option for individuals seeking effective and reliable sleep aids.

Melatonin manufacturers | traders | suppliers

We have 10 companies offering Melatonin produced in 5 different countries.

Get in contact with the supplier of your choice:

  • Sinoway industrial Co.,Ltd from China, product country of origin China
  • Xi'an Tian Guangyuan Biotech Co.,Ltd from China, product country of origin China
  • LGM Pharma from United States, product country of origin World
  • Shandong Octagon Chemicals Limited from China, product country of origin China
  • Aurora Industry Co., Ltd from China, product country of origin China
  • SETV Global from India, product country of origin India
  • Caesar & Loretz GmbH (CAELO) from Germany, product country of origin Unknown
  • Duchefa Farma B.V. from Netherlands, product country of origin India
  • Flamma from Italy, product country of origin Italy
  • Flavine from Germany, product country of origin Unknown

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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