Sildenafil citrate API Manufacturers

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Located in:

Poland

Producer

Produced in:

Poland

Established in: 1951

MOQ: -

Employees: 455+

Largest Polish manufacturer of pharmaceuticals and a leader of the Polish pharmaceutical market.

FDA approved european manufcaturing facilities

Export APIs to more than 60 countries worldwide

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Located in:

China

Established for 17 years and a leading enterprise in China's API industry

Mature technology and advanced production equipment

Quality assurance and fast delivery

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    Produced in:

    Unknown

    Established in: 1886

    MOQ: -

    Employees: 275+

    Raw materials, CMO and OTC products

    Two GMP certified locations

    Customisable (small-sized) packages

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    Produced in:

    China

    Established in: 2011

    MOQ: 1 kg

    Employees: 10+

    Fast Response and Good Communication

    Willingness To Start From Small

    Flexible Payment Terms

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    Located in:

    China

    Passed ISO9001:2015 and SGS audit

    Provide one-stop CDMO service from R&D to production

    Certifications: ISO9001: 2015, HALAL Certificate, Kosher Certification

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    Located in:

    Slovenia

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    China
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    Located in:

    Italy
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    Located in:

    India
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    Located in:

    India
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    Producer

    Produced in:

    Unknown

    Established in: 1944

    MOQ: -

    Employees: 4,000

    14 international API plant sites

    Portfolio of 350+ APIs

    Teva is among the world’s largest generic drug/API manufacturers

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    Looking for Sildenafil citrate API 171599-83-0?

    Description:
    Here you will find a list of producers, manufacturers and traders of Sildenafil citrate. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
    API | Excipient name:
    Sildenafil citrate 
    Synonyms:
    Sildenafil citras  
    Cas Number:
    171599-83-0 
    DrugBank number:
    DBSALT000347 
    Unique Ingredient Identifier:
    BW9B0ZE037

    Sildenafil citrate is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. 
     

    Sildenafil citrate is a type of Phosphodiesterase-5 inhibitors


    Phosphodiesterase-5 inhibitors are a subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that are widely used in the treatment of various medical conditions. These inhibitors target the enzyme phosphodiesterase-5, which plays a crucial role in the regulation of cyclic guanosine monophosphate (cGMP) levels in the body.

    By inhibiting phosphodiesterase-5, these APIs effectively increase the concentration of cGMP in certain tissues and organs, leading to several beneficial effects. One of the most well-known applications of phosphodiesterase-5 inhibitors is in the treatment of erectile dysfunction (ED). These medications, such as sildenafil, tadalafil, and vardenafil, work by enhancing the blood flow to the penile tissues, promoting and sustaining erections.

    Phosphodiesterase-5 inhibitors also find applications in the treatment of pulmonary arterial hypertension (PAH). By dilating the blood vessels in the lungs, these APIs reduce the workload on the heart and improve exercise capacity in PAH patients. Furthermore, they are being explored for their potential benefits in other areas, such as the treatment of Raynaud's disease and altitude sickness.

    It is important to note that phosphodiesterase-5 inhibitors should be used under medical supervision, as they can interact with other medications and have potential side effects. Common side effects include headache, flushing, nasal congestion, and gastrointestinal disturbances.

    In summary, phosphodiesterase-5 inhibitors are a class of pharmaceutical APIs that are widely utilized for the treatment of erectile dysfunction and pulmonary arterial hypertension. Their ability to selectively inhibit phosphodiesterase-5 and modulate cGMP levels makes them valuable therapeutic agents in managing these conditions.


    Sildenafil citrate (Phosphodiesterase-5 inhibitors), classified under Genitourinary Agents


    Genitourinary agents are a category of pharmaceutical active ingredients (APIs) that are specifically designed to target and treat disorders related to the genitourinary system. The genitourinary system encompasses the organs and structures involved in the production, storage, and elimination of urine, as well as the reproductive organs.

    These APIs play a crucial role in the treatment of various genitourinary conditions, including urinary tract infections (UTIs), erectile dysfunction, urinary incontinence, benign prostatic hyperplasia (BPH), and other related disorders. They exert their therapeutic effects by interacting with specific receptors or enzymes in the genitourinary system, regulating physiological processes, and restoring normal function.

    Some commonly used genitourinary agents include alpha-blockers, which relax the smooth muscles in the prostate and bladder neck, improving urine flow in patients with BPH. Additionally, phosphodiesterase type 5 inhibitors (PDE5 inhibitors) are widely prescribed for erectile dysfunction, as they enhance blood flow to the penile tissues, facilitating erection.

    These APIs are typically formulated into various dosage forms, such as tablets, capsules, creams, gels, or injections, allowing for convenient administration to patients. The development and production of genitourinary agents involve stringent quality control measures and compliance with regulatory guidelines to ensure safety, efficacy, and consistent product performance.

    In summary, genitourinary agents form a crucial category of pharmaceutical APIs used to treat a range of disorders affecting the genitourinary system. Their targeted mechanisms of action and diverse dosage forms make them valuable tools in improving genitourinary health and enhancing patients' quality of life.



    Sildenafil citrate manufacturers | traders | suppliers

    We have 23 companies offering Sildenafil citrate produced in 7 different countries.

    Get in contact with the supplier of your choice:

    • Polpharma from Poland, product country of origin Poland
    • Xi'an ZB Biotech Co., Ltd from China, product country of origin China
    • Caesar & Loretz GmbH (CAELO) from Germany, product country of origin Unknown
    • Shandong Octagon Chemicals Limited from China, product country of origin China
    • Sinoway industrial Co.,Ltd from China, product country of origin China
    • KRKA from Slovenia, product country of origin Slovenia
    • Hebei Changshan Bio. from China, product country of origin China
    • Bioindustria from Italy, product country of origin Italy
    • Aquatic Remedies Pvt Ltd from India, product country of origin India
    • Amoli Organics from India, product country of origin India
    • Torrent Pharma from India, product country of origin India
    • Raks Pharma from India, product country of origin India
    • Jestin healthcare from India, product country of origin India
    • Changzhou Yabang from China, product country of origin China
    • Teva API from Israel, product country of origin Unknown
    • Teva (Hangzhou) from China, product country of origin China
    • Jinan Mingxin from China, product country of origin China
    • Maprimed from Argentina, product country of origin Argentina
    • Aarambh Life Science from India, product country of origin India
    • Phalanx Labs from India, product country of origin India
    • Mylan from India, product country of origin India
    • Hetero Drugs from India, product country of origin Unknown
    • MSN Organics from India, product country of origin India

    Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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