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Somatostatin
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Established in: 2019
MOQ: 1 g
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Looking for Somatostatin API 38916-34-6?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Somatostatin. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Somatostatin
- Cas Number:
- 38916-34-6
- DrugBank number:
- DB09099
- Unique Ingredient Identifier:
- 6E20216Q0L
About Somatostatin
It's time for some technical information for the ones who understand chemistry: Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues 9 that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating hormones from the anterior pituitary Somatostatin is initially secreted as a 116 amino acid precursor, preprosomatostatin, which undergoes endoproteolytic cleavage to prosomastatin. Prosomastatin is further process into two active forms, somatostatin-14 (SST-14) and somatostatin-28 (SST-28), an extended SST-14 sequence to the N-terminus The actions of somatostatin are mediated via signalling pathways of G protein-coupled somatostatin receptors. Antineoplastic effects and potential uses of somatostatin on various tumours, including pituitary adenomas, GEP-NETs, paragangliomas, carcinoids, breast cancers, malignant lymphoma and small-cell lung cancers, have been extensively investigated.
More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.
Somatostatin is a type of Somatostatin Analogs
Somatostatin analogs are a subcategory of pharmaceutical active pharmaceutical ingredients (APIs) used in the treatment of various medical conditions. These analogs are synthetic versions of somatostatin, a hormone naturally produced in the body.
Somatostatin analogs are primarily used in the management of conditions such as acromegaly, a hormonal disorder characterized by excessive growth hormone production, and neuroendocrine tumors (NETs), which are tumors that arise from the neuroendocrine cells.
These analogs function by mimicking the actions of somatostatin in the body. Somatostatin normally inhibits the release of several hormones, including growth hormone, insulin, glucagon, and gastrin. By imitating somatostatin's inhibitory effects, somatostatin analogs help regulate the production and release of these hormones.
One commonly used somatostatin analog is octreotide, which is available in various formulations, including injectable and long-acting depot formulations. Octreotide is administered to control symptoms associated with acromegaly and NETs, such as excessive growth, hormone overproduction, and tumor growth.
Other somatostatin analogs like lanreotide and pasireotide have also been developed and are used for similar indications. These analogs offer an extended duration of action and can be administered via subcutaneous injections.
In summary, somatostatin analogs are a crucial category of APIs utilized in the management of conditions like acromegaly and neuroendocrine tumors. They act by replicating the inhibitory effects of somatostatin and are available in various formulations to meet different patient needs. Octreotide, lanreotide, and pasireotide are examples of commonly used somatostatin analogs in clinical practice.
Somatostatin (Somatostatin Analogs), classified under Hormonal Agents
Hormonal agents are a prominent category of pharmaceutical active pharmaceutical ingredients (APIs) widely used in the medical field. These substances play a crucial role in regulating and modulating hormonal functions within the body. Hormonal agents are designed to mimic or manipulate the effects of naturally occurring hormones, allowing healthcare professionals to treat various endocrine disorders and hormonal imbalances.
Hormonal agents are commonly employed in the treatment of conditions such as hypothyroidism, hyperthyroidism, diabetes, and hormonal cancers. These APIs work by interacting with specific hormone receptors, either by stimulating or inhibiting their activity, to restore the balance of hormones in the body. They can be administered orally, intravenously, or through other routes depending on the specific medication and patient needs.
Pharmaceutical companies employ rigorous manufacturing processes and quality control measures to ensure the purity, potency, and safety of hormonal agent APIs. These APIs are synthesized using chemical or biotechnological methods, often starting from natural hormone sources or through recombinant DNA technology. Stringent regulatory guidelines are in place to guarantee the efficacy and safety of hormonal agent APIs, ensuring that patients receive high-quality medications.
As the demand for hormone-related therapies continues to grow, ongoing research and development efforts focus on enhancing the effectiveness and reducing the side effects of hormonal agent APIs. This includes the exploration of novel delivery systems, advanced formulations, and targeted drug delivery methods. By continuously advancing our understanding and capabilities in hormonal agents, the medical community can improve patient outcomes and quality of life for individuals with hormonal disorders.
Somatostatin manufacturers | traders | suppliers
We have 6 companies offering Somatostatin produced in 5 different countries.
Get in contact with the supplier of your choice:
- Apino Pharma Co., Ltd. from China, product country of origin China
- Hemmo Pharma from India, product country of origin India
- BCN Peptides from Spain, product country of origin Spain
- Socosur from France, product country of origin Unknown
- Hainan Shuangcheng from China, product country of origin China
- Polypeptide Labs from Sweden, product country of origin Sweden
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