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Aprepitant API Manufacturers & Suppliers

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Description:

Here you will find a list of producers, manufacturers and distributors of Aprepitant. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.

API | Excipient name:

Aprepitant 

Synonyms:

Aprepitant , Aprepitantum  

Cas Number:

170729-80-3 

DrugBank number:

DB00673 

Unique Ingredient Identifier:

1NF15YR6UY

Aprepitant is a type of Antiemetics

Antiemetics are a crucial category of pharmaceutical Active Pharmaceutical Ingredients (APIs) used to alleviate and prevent nausea and vomiting, also known as emesis. They play a vital role in managing these distressing symptoms, which can be caused by various factors such as chemotherapy, postoperative recovery, motion sickness, or gastrointestinal disorders.

Antiemetics work by targeting specific pathways in the body that trigger emesis. One common mechanism involves blocking dopamine receptors in the brain, as dopamine plays a significant role in triggering the vomiting reflex. This class of antiemetics is known as dopamine antagonists. Another mechanism involves inhibiting serotonin receptors, which are associated with nausea and vomiting. These agents, called serotonin antagonists, effectively reduce these symptoms.

In addition to dopamine and serotonin antagonists, other types of antiemetics include neurokinin-1 receptor antagonists, antihistamines, and anticholinergics. Each of these classes acts on different pathways in the body to provide relief from nausea and vomiting.

Pharmaceutical companies manufacture antiemetic APIs in accordance with strict quality control guidelines and regulations. These APIs serve as the active ingredients in various formulations, such as tablets, capsules, injections, or suppositories, designed to deliver the desired therapeutic effects.

Overall, antiemetic APIs form an essential category in the pharmaceutical industry, addressing the significant need for effective management of nausea and vomiting. Their development and availability greatly contribute to enhancing patient comfort and quality of life during various medical treatments and conditions.

• Jubilant Pharmova from India, product country of origin India
• Apino Pharma Co., Ltd. from China, product country of origin China
• Shandong Octagon Chemicals Limited from China, product country of origin China
• LGM Pharma from United States, product country of origin World
• Aurora Industry Co., Ltd from China, product country of origin China
• SETV Global from India, product country of origin India
• Wisdom Pharma from China, product country of origin China
• TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
• Sandoz from Austria, product country of origin India
• Piramal Pharma Solutions from India, product country of origin India
• Optimus Drugs Pvt Ltd from India, product country of origin India
• Hetero Drugs from India, product country of origin India
• Siegfried from Germany, product country of origin Unknown
• Piramal Healthcare from United Kingdom, product country of origin India
• MSN Pharma from India, product country of origin India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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