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Drotaverine
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Established in: 2021
MOQ: -
Employees: 19
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Looking for Drotaverine API 14009-24-6?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Drotaverine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Drotaverine
- Synonyms:
- Drotin , Drotaverin
- Cas Number:
- 14009-24-6
- DrugBank number:
- DB06751
- Unique Ingredient Identifier:
- 98QS4N58TW
About Drotaverine
So, what does it do? Drotaverine (INN, also known as drotaverin) is an antispasmodic drug, structurally related to papaverine. Drotaverine is a selective inhibitor of phosphodiesterase, and has no anticholinergic effects. Drotaverine has been shown to possess dose-dependant analgesic effects in animal models. One small study has shown drotaverine to be eliminated mainly non-renally.
More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.
Drotaverine is a type of Musculotropic spasmolytics
Musculotropic spasmolytics are a subcategory of pharmaceutical Active Pharmaceutical Ingredients (APIs) used to alleviate muscle spasms and related conditions. These medications primarily target smooth muscles, such as those found in the gastrointestinal tract, urinary bladder, and blood vessels.
Musculotropic spasmolytics exert their therapeutic effects by acting on the muscarinic receptors in smooth muscle cells. By blocking the binding of acetylcholine to these receptors, they inhibit the excessive contractions that cause muscle spasms. This leads to muscle relaxation, pain relief, and improved functionality.
These APIs are commonly prescribed for various conditions characterized by muscle spasms, such as irritable bowel syndrome, urinary incontinence, and peripheral vascular diseases. They can also be employed as premedication for certain diagnostic procedures, such as endoscopies or cystoscopies, to reduce discomfort and facilitate examination.
Musculotropic spasmolytics encompass several well-known drugs, including butylscopolamine, hyoscine, and dicyclomine. These medications are available in different formulations, such as tablets, capsules, or injectables, allowing for convenient administration.
As with any pharmaceutical treatment, musculotropic spasmolytics may have potential side effects. These can include dry mouth, blurred vision, dizziness, constipation, and urinary retention. It is essential for healthcare professionals to carefully evaluate each patient's medical history and prescribe the appropriate dosage to minimize adverse effects.
In conclusion, musculotropic spasmolytics are a vital subclass of pharmaceutical APIs that effectively address muscle spasms. By selectively targeting smooth muscle cells and inhibiting excessive contractions, these medications provide relief and enhance the quality of life for individuals suffering from various conditions involving muscle spasms.
Drotaverine (Musculotropic spasmolytics), classified under Autonomic Nervous System Agents
Autonomic Nervous System Agents are a crucial category of pharmaceutical active ingredients (APIs) that target the autonomic nervous system (ANS). The ANS plays a vital role in regulating essential bodily functions such as heart rate, blood pressure, digestion, and respiratory rate. This category of pharmaceutical APIs encompasses a wide range of drugs designed to modulate the activity of the ANS.
One subcategory within Autonomic Nervous System Agents is the Sympathomimetic agents, which mimic the effects of the sympathetic nervous system. These drugs are often used to treat conditions such as asthma, nasal congestion, and hypotension by stimulating specific adrenergic receptors.
Conversely, Sympatholytic agents act to inhibit or block the sympathetic nervous system. They are employed to treat hypertension, anxiety, and certain cardiac conditions by reducing sympathetic activity.
Another subcategory is Parasympathomimetic agents, which mimic the effects of the parasympathetic nervous system. These drugs are commonly used to treat glaucoma, urinary retention, and certain gastrointestinal disorders by stimulating cholinergic receptors.
Parasympatholytic agents, on the other hand, act to block the parasympathetic nervous system. They find applications in the treatment of conditions such as overactive bladder and irritable bowel syndrome by inhibiting cholinergic receptors.
The Autonomic Nervous System Agents API category includes various drugs with distinct mechanisms of action that enable healthcare professionals to fine-tune the balance of the autonomic nervous system. By targeting specific receptors and pathways, these pharmaceutical APIs provide valuable therapeutic options for managing a wide range of medical conditions related to autonomic dysfunction.
Drotaverine manufacturers | traders | suppliers
We have 4 companies offering Drotaverine produced in 1 different countries.
Get in contact with the supplier of your choice:
- SETV Global from India, product country of origin India
- Suryakala Laboratories Pvt Ltd from India, product country of origin India
- Punjab Chemicals & Crop from India, product country of origin India
- Synthokem Labs from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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