Autonomic Nervous System Agents


Autonomic Nervous System Agents are a crucial category of pharmaceutical active ingredients (APIs) that target the autonomic nervous system (ANS). The ANS plays a vital role in regulating essential bodily functions such as heart rate, blood pressure, digestion, and respiratory rate. This category of pharmaceutical APIs encompasses a wide range of drugs designed to modulate the activity of the ANS.

One subcategory within Autonomic Nervous System Agents is the Sympathomimetic agents, which mimic the effects of the sympathetic nervous system. These drugs are often used to treat conditions such as asthma, nasal congestion, and hypotension by stimulating specific adrenergic receptors.

Conversely, Sympatholytic agents act to inhibit or block the sympathetic nervous system. They are employed to treat hypertension, anxiety, and certain cardiac conditions by reducing sympathetic activity.

Another subcategory is Parasympathomimetic agents, which mimic the effects of the parasympathetic nervous system. These drugs are commonly used to treat glaucoma, urinary retention, and certain gastrointestinal disorders by stimulating cholinergic receptors.

Parasympatholytic agents, on the other hand, act to block the parasympathetic nervous system. They find applications in the treatment of conditions such as overactive bladder and irritable bowel syndrome by inhibiting cholinergic receptors.

The Autonomic Nervous System Agents API category includes various drugs with distinct mechanisms of action that enable healthcare professionals to fine-tune the balance of the autonomic nervous system. By targeting specific receptors and pathways, these pharmaceutical APIs provide valuable therapeutic options for managing a wide range of medical conditions related to autonomic dysfunction.

NameCAS numberCategoryAmount of suppliers
Aclidinium727649-81-2Anticholinergics/Parasympathemimetics1
Atropine51-55-8Anticholinergics/Parasympathemimetics26
Benzatropine86-13-5Anticholinergics/Parasympathemimetics7
Bethanechol674-38-4Parasympathomimetics7
Biperiden514-65-8Anticholinergics/Parasympathemimetics7
Carbachol51-83-2Parasympathomimetics2
Cevimeline107233-08-9Parasympathomimetics8
Cholinhydrogentartrat87-67-2Parasympathomimetics1
Cimetropium Bromide51598-60-8Anticholinergics/Parasympathemimetics3
Clidinium7020-55-5Anticholinergics/Parasympathemimetics4
Cyclopentolate512-15-2Anticholinergics/Parasympathemimetics9
Darifenacin133099-04-4Anticholinergics/Parasympathemimetics18
Dicyclomine77-19-0Anticholinergics/Parasympathemimetics8
Drotaverine14009-24-6Musculotropic spasmolytics5
Fesoterodine286930-02-7Anticholinergics/Parasympathemimetics15
Flavoxate15301-69-6Anticholinergics/Parasympathemimetics12
Glycopyrronium Bromide740028-90-4Anticholinergics/Parasympathemimetics16
Homatropine HydrobromideAnticholinergics/Parasympathemimetics2
Homatropine Methylbromide80-49-9Anticholinergics/Parasympathemimetics10
Hyoscyamine101-31-5Anticholinergics/Parasympathemimetics6
Imidafenacin170105-16-5Anticholinergics/Parasympathemimetics3
Ipratropium Bromide22254-24-6Anticholinergics/Parasympathemimetics20
Ipratropium Impurity E22235-74-1Anticholinergics/Parasympathemimetics1
Isopropamide7492-32-2Anticholinergics/Parasympathemimetics4
Mepenzolate25990-43-6Anticholinergics/Parasympathemimetics1
Methacholine55-92-5Parasympathomimetics4
Methylscopolamine bromide155-41-9Anticholinergics/Parasympathemimetics6
Oxybutynin5633-20-5Anticholinergics/Parasympathemimetics14
Pilocarpine92-13-7Parasympathomimetics6
Pilocarpine hydrochlorideParasympathomimetics5
Pirenzepine28797-61-7Anticholinergics/Parasympathemimetics4
PridinolAnticholinergics/Parasympathemimetics1
Propantheline298-50-0Anticholinergics/Parasympathemimetics1
Pyridostigmine155-97-5Anticholinergics/Parasympathemimetics9
Scopolamine51-34-3Anticholinergics/Parasympathemimetics13
Scopolamine butylbromide149-64-4Anticholinergics/Parasympathemimetics11
Tiotropium186691-13-4Anticholinergics/Parasympathemimetics16
Tropicamide1508-75-4Anticholinergics/Parasympathemimetics10
Trospium47608-32-2Musculotropic spasmolytics14
Umeclidinium869185-19-3Anticholinergics/Parasympathemimetics2