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Clofazimine
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Looking for Clofazimine API 2030-63-9?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Clofazimine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Clofazimine
- Synonyms:
- Clofazimin , Clofazimina , Clofazimine , Clofaziminum , Lamprene , Riminophenazine
- Cas Number:
- 2030-63-9
- DrugBank number:
- DB00845
- Unique Ingredient Identifier:
- D959AE5USF
About Clofazimine
You can find a short description about Clofazimine here. Clofazimine is a highly lipophilic antimicrobial riminophenazine dye used in combination with other agents, such as dapsone, for the treatment of leprosy. It was originally described in 1957 and was the prototypical riminophenazine dye - a bright-red dye that, in its clinical use, results in long-lasting discoloration of the skin and bodily fluids. Although it carries in vitro activity against other mycobacterium, such as Mycobacterium tuberculosis, it is generally considered an ineffective treatment in comparison to classic tuberculosis treatments such as rifampicin and isoniazid.
You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet and DMF.
Clofazimine is a type of Other antibacterials
The Other Antibacterials subcategory within the pharmaceutical Active Pharmaceutical Ingredients (APIs) encompasses a diverse range of compounds used to combat bacterial infections. These antibacterials possess unique mechanisms of action, making them valuable tools in the fight against drug-resistant bacteria.
One class of Other Antibacterials is the cyclic lipopeptides, which include compounds such as daptomycin. These lipopeptides disrupt bacterial cell membranes, leading to cell death. They have demonstrated efficacy against a broad spectrum of Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA).
Another group of antibacterials in this subcategory is the nitroimidazoles. Metronidazole is a well-known representative of this class and is effective against anaerobic bacteria and protozoa. Nitroimidazoles exert their antibacterial activity by damaging DNA and disrupting essential cellular processes.
The polymyxins, such as polymyxin B and colistin, are also part of the Other Antibacterials group. These cyclic polypeptides possess a unique mechanism of action, targeting bacterial cell membranes and causing leakage, ultimately leading to cell death. Polymyxins are particularly effective against Gram-negative bacteria, including multidrug-resistant strains like carbapenem-resistant Enterobacteriaceae (CRE).
Furthermore, some miscellaneous antibacterials fall under this subcategory. For instance, fosfomycin, a phosphonic acid derivative, inhibits bacterial cell wall synthesis. Fosfomycin has shown efficacy against both Gram-positive and Gram-negative pathogens, including urinary tract infections caused by multidrug-resistant bacteria.
Clofazimine (Other antibacterials ), classified under Antibacterials
Antibacterials, a category of pharmaceutical active pharmaceutical ingredients (APIs), play a crucial role in combating bacterial infections. These APIs are chemical compounds that target and inhibit the growth or kill bacteria, helping to eliminate harmful bacterial pathogens from the body.
Antibacterials are essential for the treatment of various bacterial infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and more. They are commonly prescribed by healthcare professionals to combat both mild and severe bacterial infections.
Within the category of antibacterials, there are different classes and subclasses of APIs, each with distinct mechanisms of action and target bacteria. Some commonly used antibacterials include penicillins, cephalosporins, tetracyclines, macrolides, and fluoroquinolones. These APIs work by interfering with various aspects of bacterial cellular processes, such as cell wall synthesis, protein synthesis, DNA replication, or enzyme activity.
The development and production of antibacterial APIs require stringent quality control measures to ensure their safety, efficacy, and purity. Pharmaceutical manufacturers must adhere to Good Manufacturing Practices (GMP) and follow rigorous testing protocols to guarantee the quality and consistency of these APIs.
As bacterial resistance to antibiotics continues to be a significant concern, ongoing research and development efforts aim to discover and develop new antibacterial APIs. The evolution of antibacterials plays a crucial role in combating emerging bacterial strains and ensuring effective treatment options for infectious diseases.
In summary, antibacterials are a vital category of pharmaceutical APIs used to treat bacterial infections. They are designed to inhibit or kill bacteria, and their development requires strict adherence to quality control standards. By continually advancing research in this field, scientists and pharmaceutical companies can contribute to the ongoing battle against bacterial infections.
Clofazimine manufacturers | traders | suppliers
We have 3 companies offering Clofazimine produced in 3 different countries.
Get in contact with the supplier of your choice:
- Sangrose Labs. from India, product country of origin India
- Sandoz from Austria, product country of origin Unknown
- Derivados Quimicos from Spain, product country of origin Spain
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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