Vericiguat API Manufacturers

Looking for Vericiguat API 1350653-20-1?

Description:

Here you will find a list of producers, manufacturers and distributors of Vericiguat. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.

API | Excipient name:

Vericiguat 

Synonyms:

Vericiguatum  

Cas Number:

1350653-20-1 

DrugBank number:

DB15456 

Unique Ingredient Identifier:

LV66ADM269

Vericiguat is a type of sGC stimulator

The sGC stimulator is a pharmaceutical API (Active Pharmaceutical Ingredient) that falls under the subcategory of soluble guanylate cyclase stimulators. It is an innovative therapeutic agent that has gained significant attention in the field of cardiovascular medicine.

sGC stands for soluble guanylate cyclase, which is an enzyme found in various tissues throughout the body, including blood vessels and the heart. This enzyme plays a crucial role in regulating the production of cyclic guanosine monophosphate (cGMP), a signaling molecule involved in smooth muscle relaxation and vasodilation.

sGC stimulators work by directly activating the sGC enzyme, leading to increased production of cGMP. This, in turn, promotes relaxation of smooth muscles in blood vessels, resulting in vasodilation and improved blood flow. By enhancing the activity of sGC, these stimulators provide a unique mechanism of action for treating cardiovascular diseases, such as pulmonary hypertension and heart failure.

Pharmaceutical companies have been actively researching and developing sGC stimulators as potential therapeutic options. These APIs offer promising benefits, including improved exercise capacity, reduced symptoms, and enhanced quality of life for patients with cardiovascular conditions.

As the pharmaceutical industry continues to advance, sGC stimulators hold great promise for the treatment of various cardiovascular disorders. Their targeted mechanism of action and potential positive impact on patient outcomes make them a valuable addition to the arsenal of medications available to healthcare professionals.

Vericiguat (sGC stimulator), classified under Antihypertensive agents

Antihypertensive agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat high blood pressure, also known as hypertension. These medications are designed to lower blood pressure and reduce the risk of associated cardiovascular complications.

Antihypertensive agents function by targeting various mechanisms involved in blood pressure regulation. Some common classes of antihypertensive agents include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), beta-blockers, calcium channel blockers (CCBs), and diuretics.

ACE inhibitors work by inhibiting the enzyme responsible for converting angiotensin I to angiotensin II, a hormone that constricts blood vessels. ARBs, on the other hand, block the receptors to which angiotensin II binds, thereby preventing its vasoconstrictive effects.

Beta-blockers reduce blood pressure by blocking the effects of adrenaline and noradrenaline, which are responsible for increasing heart rate and constricting blood vessels. CCBs inhibit calcium from entering the smooth muscles of blood vessels, resulting in relaxation and vasodilation. Diuretics promote the elimination of excess fluid and sodium from the body, reducing blood volume and thereby lowering blood pressure.

Antihypertensive agents are typically prescribed based on the individual patient's condition and specific needs. They can be used alone or in combination to achieve optimal blood pressure control. It is important to note that antihypertensive agents should be taken regularly as prescribed by a healthcare professional and may require periodic monitoring to ensure their effectiveness and manage any potential side effects.

In summary, antihypertensive agents play a vital role in the management of hypertension by targeting various mechanisms involved in blood pressure regulation. These medications offer significant benefits in reducing the risk of cardiovascular complications associated with high blood pressure.

• Senova Technology Co., Ltd. from China, product country of origin China
• Sichuan Elixir Pharmaceutical Co., Ltd from China, product country of origin China
• Apino Pharma Co., Ltd. from China, product country of origin China

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