Empagliflozin API Manufacturers

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TOP RANKING

Located in:

Poland

Producer

Produced in:

Poland

Established in: 1951

MOQ: -

Employees: 455+

Largest Polish manufacturer of pharmaceuticals and a leader of the Polish pharmaceutical market.

FDA approved european manufcaturing facilities

Export APIs to more than 60 countries worldwide

  • CoA

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Located in:

China

Produced in:

China

Established in: 1987

MOQ: -

Passed ISO9001:2015 and SGS audit

Provide one-stop CDMO service from R&D to production

Certifications: ISO9001: 2015, HALAL Certificate, Kosher Certification

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TOP RANKING

Located in:

India

Produced in:

India

Established in: 1984

MOQ: -

Employees: 2000+

Vertically integrated company

Largest producer of Montelukast in the world

USFDA & WHO GMP approved API plants

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HIGHLIGHTED

Located in:

India

Produced in:

China

MOQ: 1 kg

  • CoA

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HIGHLIGHTED

Located in:

China

Produced in:

China

Established in: 2013

MOQ: 100 g

Employees: 25+

ISO9001 certified

Drug R&D center (in Hangzhou)

From lab scale (mg/g) to commercial scale (kgs/tons)

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HIGHLIGHTED

Located in:

China

Produced in:

China

Established in: 2008

MOQ: -

Employees: 300+

More than 150 patents based on independent intelligence

Expertise in anti-tumor, anti-diabetes and cardiovascular API and intermediates.

GMP facility with annual production capacity of 300M

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HIGHLIGHTED

Located in:

United States

Produced in:

United States

Established in: 1994

MOQ: -

Employees: 50+

26+ years of distribution expertise with regulatory excellence

16 worldwide locations supplying high quality ingredients

All our manufacturer partners are cGMP complaint

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Produced in:

China

Established in: 2019

MOQ: 1 kg

Employees: 10+

Focused on pharmaceutical industry

Reasonable price for the customers

Full service from R&D stage to commercial stage

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  • + 0

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  • CoA

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Producer

Produced in:

Turkey

Established in: 2022

MOQ: -

Employees: 100+

Operating on GMP guidelines with the most recent technologies and equipment

High-quality products at unrivaled prices

Specialize in Narcotic and Non-Narcotic APIs

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Located in:

China

Produced in:

China

MOQ: -

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Replies slower than most

Located in:

India

Producer

Produced in:

India

MOQ: -

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  • DMF

  • CoA

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Located in:

China

Produced in:

China

MOQ: -

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  • CoA

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Producer

Produced in:

Unknown

Established in: 1944

MOQ: -

Employees: 4,000

14 international API plant sites

Portfolio of 350+ APIs

Teva is among the world’s largest generic drug/API manufacturers

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  • CoA

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Located in:

India

Producer

Produced in:

India

MOQ: -

  • CoA

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Replies slower than most

Located in:

China

Producer

Produced in:

China

MOQ: -

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Replies slower than most

Located in:

China

Produced in:

China

MOQ: -

  • CoA

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  • coa

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Replies slower than most

Located in:

Malta

Produced in:

Malta

MOQ: -

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Located in:

Italy

Producer

Produced in:

Italy

MOQ: -

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Located in:

India

Producer

Produced in:

India

MOQ: -

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  • DMF

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  • CoA

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Replies slower than most

Located in:

China

Produced in:

China

MOQ: -

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  • DMF

  • CoA

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Replies slower than most

Located in:

India

Producer

Produced in:

India

MOQ: -

  • CoA

  • GMP

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  • FDA

  • DMF

  • + 0

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  • DMF

  • CoA

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Replies slower than most

Located in:

India

Producer

Produced in:

India

MOQ: -

  • CoA

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  • CEP

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  • DMF

  • + 0

All certificates

  • DMF

  • CoA

Located in:

India

Produced in:

India

MOQ: -

  • CoA

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  • CEP

  • FDA

  • DMF

  • + 0

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  • DMF

  • CoA

Located in:

India

Producer

Produced in:

India

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

Located in:

India

Producer

Produced in:

India

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

Located in:

Germany

Produced in:

Germany

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • CoA

Located in:

China

Produced in:

China

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • coa

Located in:

India

Produced in:

India

MOQ: -

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • coa

  • ISO

  • EDQM certificate 2017

  • FDA

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Looking for Empagliflozin API 864070-44-0?

Description:
Here you will find a list of producers, manufacturers and distributors of Empagliflozin. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Empagliflozin 
Synonyms:
 
Cas Number:
864070-44-0 
DrugBank number:
DB09038 
Unique Ingredient Identifier:
HDC1R2M35U

About Empagliflozin

So, what does it do? Empagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily responsible for the reabsorption of glucose in the kidney. It is used clinically as an adjunct to diet and exercise, often in combination with other drug therapies for the management of type 2 diabetes mellitus. The first known inhibitor of SGLTs, phlorizin, was isolated from the bark of apple trees in 1835 and researched extensively into the 20th century, but was ultimately deemed inappropriate for clinical use given its lack of specificity and significant gastrointestinal side effects.

Not sure if this is the exact product you're looking for? Contact the supplier by using the send inquiry button.

Empagliflozin is a type of SGLT2-inhibitors


SGLT2 inhibitors, short for Sodium-Glucose Co-Transporter 2 inhibitors, belong to the pharmaceutical API subcategory utilized in the treatment of type 2 diabetes mellitus (T2DM). These innovative drugs target the SGLT2 protein responsible for reabsorbing glucose in the kidneys, resulting in increased urinary glucose excretion.

By inhibiting SGLT2, these drugs effectively lower blood glucose levels and improve glycemic control in patients with T2DM. This mechanism of action is independent of insulin secretion or sensitivity, making SGLT2 inhibitors an attractive option for individuals who are resistant to or cannot tolerate other diabetes medications.

Some commonly prescribed SGLT2 inhibitors include canagliflozin, dapagliflozin, and empagliflozin. These pharmaceutical APIs are typically formulated into oral tablets, making them convenient for patient administration.

Clinical studies have demonstrated the effectiveness of SGLT2 inhibitors in reducing HbA1c levels, body weight, and blood pressure in patients with T2DM. Additionally, these medications have shown potential cardiovascular benefits, including a decreased risk of cardiovascular events.

However, it is important to note that SGLT2 inhibitors are not suitable for everyone, and their use should be carefully considered in patients with renal impairment or a history of ketoacidosis. Adverse effects may include genitourinary infections and increased risk of dehydration.

Overall, SGLT2 inhibitors are a promising class of pharmaceutical APIs that offer an innovative approach to managing T2DM by targeting renal glucose reabsorption. Ongoing research and development in this field aim to further optimize the therapeutic potential of SGLT2 inhibitors and improve patient outcomes.


Empagliflozin (SGLT2-inhibitors), classified under Anti-diabetics


Anti-diabetics, belonging to the pharmaceutical API (Active Pharmaceutical Ingredient) category, are a group of compounds designed to manage and treat diabetes mellitus, a chronic metabolic disorder characterized by high blood sugar levels. These medications play a vital role in controlling diabetes and preventing complications associated with the disease.

Anti-diabetics encompass a wide range of drug classes, including biguanides, sulfonylureas, thiazolidinediones, dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium-glucose cotransporter-2 (SGLT2) inhibitors, and glucagon-like peptide-1 (GLP-1) receptor agonists. Each class works through different mechanisms to regulate blood sugar levels and improve insulin sensitivity.

Biguanides, such as metformin, reduce glucose production by the liver and enhance insulin sensitivity in peripheral tissues. Sulfonylureas, like glipizide, stimulate insulin secretion from pancreatic beta cells. Thiazolidinediones, including pioglitazone, improve insulin sensitivity in muscle and adipose tissues. DPP-4 inhibitors, such as sitagliptin, increase insulin release and inhibit glucagon secretion. SGLT2 inhibitors, like dapagliflozin, decrease renal glucose reabsorption, leading to increased urinary glucose excretion. GLP-1 receptor agonists, such as exenatide, enhance insulin secretion, suppress glucagon release, slow gastric emptying, and promote satiety.

These anti-diabetic APIs serve as the foundational ingredients for the formulation of various oral tablets, capsules, and injectable medications used in the treatment of diabetes. By targeting different aspects of glucose regulation, they help patients achieve and maintain optimal blood sugar levels, thus reducing the risk of diabetic complications, such as cardiovascular disease, neuropathy, and nephropathy.

It is crucial for healthcare professionals to prescribe and administer these anti-diabetic medications appropriately, considering factors like the patient's medical history, co-existing conditions, and potential drug interactions. Regular monitoring of blood glucose levels and close medical supervision are necessary to ensure effective diabetes management.

In conclusion, anti-diabetics form a critical category of pharmaceutical APIs used for the treatment of diabetes. These compounds, encompassing various drug classes, work through distinct mechanisms to regulate blood sugar levels and improve insulin sensitivity. By facilitating glucose control, anti-diabetic APIs help mitigate the risk of complications associated with diabetes mellitus, ultimately promoting better health outcomes for patients.



Empagliflozin manufacturers | traders | suppliers

We have 28 companies offering Empagliflozin produced in 9 different countries.

Get in contact with the supplier of your choice:

  • Polpharma from Poland, product country of origin Poland
  • Sinoway industrial Co.,Ltd from China, product country of origin China
  • Morepen Laboratories Ltd. from India, product country of origin India
  • Solfyn International LLP from India, product country of origin China
  • Senova Technology Co., Ltd. from China, product country of origin China
  • Tianjin Pharmacn Medical Technology Co., ltd from China, product country of origin China
  • Rochem International, Inc. from United States, product country of origin United States
  • Apino Pharma Co., Ltd. from China, product country of origin China
  • PluviaEndo from Turkey, product country of origin Turkey
  • Beijing Huikang Boyuan from China, product country of origin China
  • Hikal from India, product country of origin India
  • Zhejiang Hongyuan from China, product country of origin China
  • Teva API from Israel, product country of origin Unknown
  • Honour Lab from India, product country of origin India
  • ALP PHARM from China, product country of origin China
  • Jiangxi Aifeimu Technology Co Ltd from China, product country of origin China
  • Amino Chemicals from Malta, product country of origin Malta
  • Bidachem from Italy, product country of origin Italy
  • Lupin from India, product country of origin India
  • Fuxing Long Rui Pharma from China, product country of origin China
  • Laurus Labs from India, product country of origin India
  • Cipla from India, product country of origin India
  • MSN Life Sciences from India, product country of origin India
  • Mylan from India, product country of origin India
  • Sun Pharma from India, product country of origin India
  • Boehringer Ingelheim from Germany, product country of origin Germany
  • Shaoxing Hantai Pharma from China, product country of origin China
  • ZCL Chemicals from India, product country of origin India

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