Anti-diabetics


Anti-diabetics, belonging to the pharmaceutical API (Active Pharmaceutical Ingredient) category, are a group of compounds designed to manage and treat diabetes mellitus, a chronic metabolic disorder characterized by high blood sugar levels. These medications play a vital role in controlling diabetes and preventing complications associated with the disease.

Anti-diabetics encompass a wide range of drug classes, including biguanides, sulfonylureas, thiazolidinediones, dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium-glucose cotransporter-2 (SGLT2) inhibitors, and glucagon-like peptide-1 (GLP-1) receptor agonists. Each class works through different mechanisms to regulate blood sugar levels and improve insulin sensitivity.

Biguanides, such as metformin, reduce glucose production by the liver and enhance insulin sensitivity in peripheral tissues. Sulfonylureas, like glipizide, stimulate insulin secretion from pancreatic beta cells. Thiazolidinediones, including pioglitazone, improve insulin sensitivity in muscle and adipose tissues. DPP-4 inhibitors, such as sitagliptin, increase insulin release and inhibit glucagon secretion. SGLT2 inhibitors, like dapagliflozin, decrease renal glucose reabsorption, leading to increased urinary glucose excretion. GLP-1 receptor agonists, such as exenatide, enhance insulin secretion, suppress glucagon release, slow gastric emptying, and promote satiety.

These anti-diabetic APIs serve as the foundational ingredients for the formulation of various oral tablets, capsules, and injectable medications used in the treatment of diabetes. By targeting different aspects of glucose regulation, they help patients achieve and maintain optimal blood sugar levels, thus reducing the risk of diabetic complications, such as cardiovascular disease, neuropathy, and nephropathy.

It is crucial for healthcare professionals to prescribe and administer these anti-diabetic medications appropriately, considering factors like the patient's medical history, co-existing conditions, and potential drug interactions. Regular monitoring of blood glucose levels and close medical supervision are necessary to ensure effective diabetes management.

In conclusion, anti-diabetics form a critical category of pharmaceutical APIs used for the treatment of diabetes. These compounds, encompassing various drug classes, work through distinct mechanisms to regulate blood sugar levels and improve insulin sensitivity. By facilitating glucose control, anti-diabetic APIs help mitigate the risk of complications associated with diabetes mellitus, ultimately promoting better health outcomes for patients.

NameCAS numberCategoryAmount of suppliersAPI market price
Aclimostat2082752-83-6Anti-diabeticsView 0 Suppliers Average price per kg: $
Albiglutide782500-75-8GLP1 agonistsView 1 Suppliers Average price per kg: $
Amylopectin9037-22-3Anti-diabeticsView 0 Suppliers Average price per kg: $
Apabetalone1044870-39-4Anti-diabeticsView 0 Suppliers Average price per kg: $
BMS-9034521339944-47-6Anti-diabeticsView 0 Suppliers Average price per kg: $
Balaglitazone199113-98-9Anti-diabeticsView 0 Suppliers Average price per kg: $
Biguanide56-03-1Anti-diabeticsView 0 Suppliers Average price per kg: $
Bisphosphocin Nu-3403717-06-6Anti-diabeticsView 0 Suppliers Average price per kg: $
Buformin692-13-7Other anti-diabeticsView 1 Suppliers Average price per kg: $
Canagliflozin842133-18-0SGLT2-inhibitorsView 30 Suppliers Average price per kg: $
Cetilistat282526-98-1Anti-diabeticsView 0 Suppliers Average price per kg: $
Chlorpropamide94-20-2SulfonylureasView 6 Suppliers Average price per kg: $
Chromium7440-47-3Anti-diabeticsView 0 Suppliers Average price per kg: $
Dapagliflozin461432-26-8SGLT2-inhibitorsView 48 Suppliers Average price per kg: $
Dapagliflozin Propanediol Monohydrate1187594-09-7SGLT2-inhibitorsView 4 Suppliers Average price per kg: $
Dihydromyricetin27200-12-0Anti-diabeticsView 1 Suppliers Average price per kg: $
Dulaglutide923950-08-7GLP1 agonistsView 2 Suppliers Average price per kg: $
Edaglitazone213411-83-7Anti-diabeticsView 0 Suppliers Average price per kg: $
Edasalonexent1204317-86-1Anti-diabeticsView 0 Suppliers Average price per kg: $
Efpeglenatide1296200-77-5Anti-diabeticsView 0 Suppliers Average price per kg: $
Elafibranor923978-27-2Anti-diabeticsView 0 Suppliers Average price per kg: $
Empagliflozin864070-44-0SGLT2-inhibitorsView 56 Suppliers Average price per kg: $
Epicatechin490-46-0Anti-diabeticsView 0 Suppliers Average price per kg: $
Ertiprotafib251303-04-5Anti-diabeticsView 0 Suppliers Average price per kg: $
Ertugliflozin1210344-57-2SGLT2-inhibitorsView 2 Suppliers Average price per kg: $
Exenatide141758-74-9GLP1 agonistsView 13 Suppliers Average price per kg: $
Fasiglifam1000413-72-8Anti-diabeticsView 0 Suppliers Average price per kg: $
Fenugreek seedOther anti-diabeticsView 1 Suppliers Average price per kg: $
Ginsenoside B252286-59-6Anti-diabeticsView 0 Suppliers Average price per kg: $
Glibenclamide10238-21-8SulfonylureasView 26 Suppliers Average price per kg: $
Gliclazide21187-98-4SulfonylureasView 28 Suppliers Average price per kg: $
Glimepiride93479-97-1SulfonylureasView 45 Suppliers Average price per kg: $
Glipizide29094-61-9SulfonylureasView 21 Suppliers Average price per kg: $
Gliquidone33342-05-1SulfonylureasView 3 Suppliers Average price per kg: $
Glyburide10238-21-8SulfonylureasView 9 Suppliers Average price per kg: $
Granotapide594842-13-4Anti-diabeticsView 0 Suppliers Average price per kg: $
Henagliflozin1623804-44-3Anti-diabeticsView 0 Suppliers Average price per kg: $
Ibipinabant464213-10-3Anti-diabeticsView 0 Suppliers Average price per kg: $
Ilacirnon1100318-47-5Anti-diabeticsView 0 Suppliers Average price per kg: $
Imiglitazar250601-04-8Anti-diabeticsView 0 Suppliers Average price per kg: $
Insulin Aspart116094-23-6InsulinView 4 Suppliers Average price per kg: $
Insulin Glargine160337-95-1InsulinView 5 Suppliers Average price per kg: $
Insulin Human11061-68-0InsulinView 3 Suppliers Average price per kg: $
Insulin Lispro133107-64-9InsulinView 2 Suppliers Average price per kg: $
Janagliflozin1800115-22-3Anti-diabeticsView 0 Suppliers Average price per kg: $
Ladarixin849776-05-2Anti-diabeticsView 0 Suppliers Average price per kg: $
Linagliptin668270-12-0DPP4-InhibitorsView 43 Suppliers Average price per kg: $
Liraglutide204656-20-2GLP1 agonistsView 25 Suppliers Average price per kg: $
Lixisenatide320367-13-3GLP1 agonistsView 3 Suppliers Average price per kg: $
MK-0767934017-32-0Anti-diabeticsView 0 Suppliers Average price per kg: $
Mannitol busulfan1187-00-4Anti-diabeticsView 0 Suppliers Average price per kg: $
Metformin657-24-9BiguanidesView 67 Suppliers Average price per kg: $
Mitoglitazone146062-49-9Anti-diabeticsView 0 Suppliers Average price per kg: $
Naveglitazar476436-68-7Anti-diabeticsView 0 Suppliers Average price per kg: $
Omarigliptin1226781-44-7Anti-diabeticsView 0 Suppliers Average price per kg: $
Pioglitazone111025-46-8GlitazonesView 38 Suppliers Average price per kg: $
Ranirestat147254-64-6Anti-diabeticsView 0 Suppliers Average price per kg: $
Razuprotafib1008510-37-9Anti-diabeticsView 0 Suppliers Average price per kg: $
Rebaudioside A58543-16-1Anti-diabeticsView 0 Suppliers Average price per kg: $
Remogliflozin etabonate442201-24-3Anti-diabeticsView 0 Suppliers Average price per kg: $
Reparixin266359-83-5Anti-diabeticsView 0 Suppliers Average price per kg: $
Saxagliptin361442-04-8DPP4-InhibitorsView 26 Suppliers Average price per kg: $
SemaglutideGLP1 agonistsView 25 Suppliers Average price per kg: $
Sitagliptin486460-32-6DPP4-InhibitorsView 57 Suppliers Average price per kg: $
Sitagliptin Phosphate654671-77-9DPP4-InhibitorsView 5 Suppliers Average price per kg: $
Sodelglitazar447406-78-2Anti-diabeticsView 0 Suppliers Average price per kg: $
Sonedenoson131865-88-8Anti-diabeticsView 0 Suppliers Average price per kg: $
Tesaglitazar251565-85-2Anti-diabeticsView 0 Suppliers Average price per kg: $
Thiazolidincarboxylic AcidGlitazonesView 5 Suppliers Average price per kg: $
Thioctic acid tromethamine137314-40-0Anti-diabeticsView 0 Suppliers Average price per kg: $
Tofogliflozin903565-83-3Anti-diabeticsView 0 Suppliers Average price per kg: $
Tolazamide1156-19-0SulfonylureasView 2 Suppliers Average price per kg: $
Tolbutamide64-77-7SulfonylureasView 5 Suppliers Average price per kg: $
Trelagliptin865759-25-7Anti-diabeticsView 1 Suppliers Average price per kg: $
Troglitazone97322-87-7GlitazonesView 1 Suppliers Average price per kg: $
Vildagliptin274901-16-5DPP4-InhibitorsView 42 Suppliers Average price per kg: $