Apremilast API Manufacturers

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TOP RANKING

Located in:

India

Produced in:

India

Established in: 1978

MOQ: -

Employees: 10k+

199 API-Related Granted Patents

Global Presence in 50+ Markets

Advanced technology and R&D Capabilities

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • GMP

  • CoA

  • ISO9001

  • MSDS

  • BSE/TSE

TOP RANKING

Located in:

Poland

Producer

Produced in:

Poland

Established in: 1951

MOQ: -

Employees: 455+

Largest Polish manufacturer of pharmaceuticals and a leader of the Polish pharmaceutical market.

FDA approved european manufcaturing facilities

Export APIs to more than 60 countries worldwide

  • CoA

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  • DMF

  • + 0

All certificates

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  • BSE/TSE

HIGHLIGHTED

Located in:

China

Produced in:

China

Established in: 2013

MOQ: 1 kg

Employees: 25+

ISO9001 certified

Drug R&D center (in Hangzhou)

From lab scale (mg/g) to commercial scale (kgs/tons)

  • CoA

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  • DMF

  • + 0

All certificates

  • CoA

  • ISO9001

  • FDA

HIGHLIGHTED

Located in:

China

Produced in:

China

Established in: 2019

MOQ: 1 kg

Employees: 10+

Focused on pharmaceutical industry

Reasonable price for the customers

Full service from R&D stage to commercial stage

  • CoA

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  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • DMF

  • MSDS

  • ISO9001

  • BSE/TSE

Produced in:

China

Established in: 1987

MOQ: -

Employees: 50+

ISO 9001:2015 & SGS audited supplier

One-stop CDMO Solutions for APl and Key intermediates

Specialized in APIs & Pharmaceutical Intermediates for 37 years

  • CoA

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  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • ISO9001

  • MSDS

Located in:

India

Produced in:

India

MOQ: -

  • CoA

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  • DMF

  • + 0

All certificates

  • DMF

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Located in:

India

Producer

Produced in:

India

MOQ: -

  • CoA

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  • + 0

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  • DMF

  • CoA

Located in:

Spain

Produced in:

Unknown

MOQ: -

  • CoA

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  • DMF

  • + 0

All certificates

  • DMF

  • CoA

  • GMP

Located in:

India

Producer

Produced in:

India

MOQ: -

  • CoA

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  • DMF

  • + 0

All certificates

  • DMF

  • CoA

Located in:

Czech Republic

Producer

Produced in:

Croatia

MOQ: -

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  • DMF

  • + 0

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Contact supplier

Replies slower than most

Producer

Produced in:

India

Established in: 1984

MOQ: -

Employees: 21,650

Diverse portfolio of 180+APIs

1754+ DMF across global markets

1100+ patents filed, and more than 70 own patents granted

  • CoA

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  • DMF

  • + 0

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  • DMF

  • WC

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  • BSE/TSE

Located in:

United Kingdom

Produced in:

Unknown

MOQ: -

  • CoA

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  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

Produced in:

Unknown

Established in: 1963

MOQ: -

Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe

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  • DMF

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  • CoA

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Located in:

India

Producer

Produced in:

India

MOQ: -

  • CoA

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  • DMF

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All certificates

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Located in:

India

Producer

Produced in:

India

MOQ: -

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All certificates

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Located in:

India

Producer

Produced in:

India

MOQ: -

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Located in:

India

Produced in:

India

MOQ: -

  • CoA

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  • DMF

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Located in:

India

Produced in:

India

MOQ: -

  • CoA

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  • + 0

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  • WC

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Located in:

Slovenia

Producer

Produced in:

India

MOQ: -

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Located in:

India

Producer

Produced in:

India

MOQ: -

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  • DMF

  • + 0

All certificates

  • DMF

  • CoA

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Looking for Apremilast API 608141-41-9?

Description:
Here you will find a list of producers, manufacturers and distributors of Apremilast. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Apremilast 
Cas Number:
608141-41-9 
DrugBank number:
DB05676 
Unique Ingredient Identifier:
UP7QBP99PN

About Apremilast

Here you will find more information about Apremilast. Apremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases. It belongs to the same drug class as Roflumilast and Crisaborole Initially approved in 2014, it is marketed by Celgene. In July 2019, apremilast was granted a new FDA approval for the treatment of oral ulcers associated with Behcet's disease, an autoimmune condition that causes recurrent skin, blood vessel, and central nervous system inflammation.

Not sure if this is the exact product you're looking for? Contact the supplier by using the send inquiry button.

Apremilast is a type of Immunosuppressants


Immunosuppressants are a vital subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that play a crucial role in medical treatments. These substances are designed to suppress or weaken the immune system's response, making them invaluable in various therapeutic applications.

Immunosuppressants find extensive use in the management of autoimmune diseases, organ transplantation, and the prevention of rejection reactions. By modulating the immune system's activity, these APIs help control excessive immune responses that can lead to tissue damage and chronic inflammation.

There are different classes of immunosuppressants, including corticosteroids, calcineurin inhibitors, antimetabolites, and biologics. Each class targets specific immune pathways to achieve the desired therapeutic effect. Corticosteroids, for instance, are known for their potent anti-inflammatory properties, making them effective in managing conditions such as rheumatoid arthritis and asthma.

Calcineurin inhibitors like cyclosporine and tacrolimus act by inhibiting the activity of calcineurin, a protein involved in immune cell activation. These drugs are commonly used in organ transplantation to prevent the immune system from attacking the transplanted organ.

Antimetabolites interfere with DNA synthesis and cell proliferation, thereby dampening immune responses. They are often prescribed for conditions like psoriasis and rheumatoid arthritis.

Biologic immunosuppressants, such as monoclonal antibodies, target specific immune cells or molecules involved in the disease process. They have revolutionized the treatment of autoimmune diseases like rheumatoid arthritis, Crohn's disease, and psoriasis.

Immunosuppressants require careful administration and monitoring due to their potential side effects and interactions with other medications. Close collaboration between healthcare professionals, pharmacists, and patients is essential to ensure the safe and effective use of these APIs in various therapeutic settings.

Overall, immunosuppressants represent a critical category of pharmaceutical APIs that significantly contribute to improving patients' quality of life by controlling the immune system's activity and managing various autoimmune conditions and transplantation outcomes.


Apremilast (Immunosuppressants), classified under Immunomodulators


Immunomodulators, a category of pharmaceutical active pharmaceutical ingredients (APIs), are substances that help regulate and modify the immune response of an individual. These compounds play a crucial role in treating various immune-related disorders and diseases. Immunomodulators work by either enhancing or suppressing the immune system, depending on the specific condition being treated.

Immunomodulators are used in the treatment of autoimmune disorders, such as rheumatoid arthritis, multiple sclerosis, and psoriasis. By suppressing the immune system, these APIs help reduce the overactive immune response associated with these conditions, thereby alleviating symptoms and preventing further damage to the body's tissues.

On the other hand, immunomodulators are also employed to boost the immune system in cases of immunodeficiency disorders. These APIs stimulate the immune response, enabling the body to better fight off infections and diseases. Additionally, immunomodulators are utilized in the prevention and treatment of organ transplant rejection, where they help modulate the immune system to accept the transplanted organ.

The development and production of immunomodulators require rigorous testing and quality control to ensure their safety and efficacy. Pharmaceutical companies carefully formulate these APIs into various dosage forms, including tablets, capsules, injections, and topical preparations, to cater to different patient needs.

In summary, immunomodulators form a vital category of pharmaceutical APIs that regulate and modify the immune system. With their ability to modulate immune responses, these compounds contribute significantly to the management and treatment of various immune-related disorders and diseases, improving the quality of life for many patients.



Apremilast manufacturers | traders | suppliers

We have 20 companies offering Apremilast produced in 5 different countries.

Get in contact with the supplier of your choice:

  • Jubilant Pharmova from India, product country of origin India
  • Polpharma from Poland, product country of origin Poland
  • Senova Technology Co., Ltd. from China, product country of origin China
  • Apino Pharma Co., Ltd. from China, product country of origin China
  • Sinoway industrial Co.,Ltd from China, product country of origin China
  • Unichem Labs. from India, product country of origin India
  • Alkem Labs. from India, product country of origin India
  • Quimica Sintetica from Spain, product country of origin Unknown
  • Raks Pharma from India, product country of origin India
  • PLIVA from Czech Republic, product country of origin Croatia
  • Dr. Reddy's from India, product country of origin India
  • Intas Pharma from United Kingdom, product country of origin Unknown
  • TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
  • Sun Pharma from India, product country of origin India
  • Cipla from India, product country of origin India
  • Mylan from India, product country of origin India
  • Hetero Drugs from India, product country of origin India
  • MSN Life Sciences from India, product country of origin India
  • Lek Pharma from Slovenia, product country of origin India
  • Lupin from India, product country of origin India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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