Immunomodulators


Immunomodulators, a category of pharmaceutical active pharmaceutical ingredients (APIs), are substances that help regulate and modify the immune response of an individual. These compounds play a crucial role in treating various immune-related disorders and diseases. Immunomodulators work by either enhancing or suppressing the immune system, depending on the specific condition being treated.

Immunomodulators are used in the treatment of autoimmune disorders, such as rheumatoid arthritis, multiple sclerosis, and psoriasis. By suppressing the immune system, these APIs help reduce the overactive immune response associated with these conditions, thereby alleviating symptoms and preventing further damage to the body's tissues.

On the other hand, immunomodulators are also employed to boost the immune system in cases of immunodeficiency disorders. These APIs stimulate the immune response, enabling the body to better fight off infections and diseases. Additionally, immunomodulators are utilized in the prevention and treatment of organ transplant rejection, where they help modulate the immune system to accept the transplanted organ.

The development and production of immunomodulators require rigorous testing and quality control to ensure their safety and efficacy. Pharmaceutical companies carefully formulate these APIs into various dosage forms, including tablets, capsules, injections, and topical preparations, to cater to different patient needs.

In summary, immunomodulators form a vital category of pharmaceutical APIs that regulate and modify the immune system. With their ability to modulate immune responses, these compounds contribute significantly to the management and treatment of various immune-related disorders and diseases, improving the quality of life for many patients.

NameCAS numberCategoryAmount of suppliers
Adenosine monophosphate61-19-8Immunostimulants2
Afimetoran2171019-55-7Immunomodulators0
Aldesleukin110942-02-4Interleukin inhibitors1
Alpha-1-proteinase inhibitor9041-92-3Immunoglobulins6
Anakinra143090-92-0Interleukin inhibitors2
Anbenitamab2367012-88-0Immunomodulators0
Andecaliximab1518996-49-0Immunomodulators0
Anselamimab2414866-63-8Immunomodulators0
Apremilast608141-41-9Immunosuppressants34
Atezolizumab1380723-44-3Monoclonal antibodies2
Avelumab1537032-82-8Monoclonal antibodies2
Azathioprine446-86-6Immunosuppressants20
Barecetamab2275727-74-5Immunomodulators0
Bepranemab2244960-75-4Immunomodulators0
Bevacizumab216974-75-3Monoclonal antibodies3
Boserolimab2444297-08-7Immunomodulators0
Briquilimab2574591-89-0Immunomodulators0
Cetuximab205923-56-4Monoclonal antibodies2
Cevostamab2249888-53-5Immunomodulators0
Cosfroviximab1792982-57-0Immunomodulators0
CpG 1018 ODN112732-17-9Immunostimulants1
CpG 7909 ODN2647530-73-0Immunostimulants1
Crefmirlimab2611099-93-3Immunomodulators0
Cyclosporine59865-13-3Immunosuppressants25
Daratumumab945721-28-8Monoclonal antibodies2
Dimethyl fumarate624-49-7Immunosuppressants39
Diroximel Fumarate1156109-27-2Immunosuppressants2
Docaravimab2247196-23-0Immunomodulators0
Eculizumab219685-50-4Immunoglobulins2
Edobacomab141410-98-2Immunomodulators0
ElafinImmunosuppressants1
Elranatamab2408850-14-4Immunomodulators0
Emerfetamab2250261-27-7Immunomodulators0
Erfonrilimab2367013-69-0Immunomodulators0
Etanercept185243-69-0Immunosuppressants3
Everolimus159351-69-6Immunosuppressants20
Exbivirumab569658-80-6Immunomodulators0
Filgotinib maleate1802998-75-9Immunomodulators2
Fingolimod162359-55-9Immunosuppressants27
Glatiramer Acetate147245-92-9Immunosuppressants16
Gresonitamab2413817-97-5Immunomodulators0
Ifinatamab deruxtecan2484870-92-8Immunomodulators0
Imiquimod99011-02-6Immunostimulants15
Ipilimumab477202-00-9Monoclonal antibodies2
Larcaviximab1792982-56-9Immunomodulators0
Leflunomide75706-12-6Immunosuppressants15
Lemzoparlimab2377483-71-9Immunomodulators0
Lenalidomide191732-72-6Immunomodulators24
Lentinan37339-90-5Immunostimulants1
Lenvervimab2055006-79-4Immunomodulators0
Libivirumab569658-79-3Immunomodulators0
Ligufalimab2428381-55-7Immunomodulators0
Marstacimab1985638-39-8Immunomodulators0
Mazorelvimab2419087-89-9Immunomodulators0
Mecbotamab vedotin2460400-64-8Immunomodulators0
Miromavimab2247163-73-9Immunomodulators0
Mycophenolate mofetil128794-94-5Immunosuppressants42
Mycophenolic acid24280-93-1Immunosuppressants15
Nivolumab946414-94-4Monoclonal antibodies2
Omalizumab242138-07-4Immunosuppressants1
Osemitamab2460539-61-9Immunomodulators0
Ozuriftamab vedotin2460400-11-5Immunomodulators0
Pagibaximab595566-61-3Immunomodulators0
Pidotimod121808-62-6Immunostimulants5
Pomalidomide19171-19-8Immunomodulators17
Porgaviximab1792982-55-8Immunomodulators0
Pucotenlimab2403647-03-8Immunomodulators0
Ramucirumab947687-13-0Monoclonal antibodies1
Ravtansine796073-69-3Monoclonal antibodies1
Rituximab174722-31-7Monoclonal antibodies5
Rivabazumab pegol1613506-32-3Immunomodulators0
Secukinumab1229022-83-6Interleukin inhibitors3
Serplulimab2231029-82-4Immunomodulators0
Sevirumab138660-96-5Immunomodulators0
Siltuximab541502-14-1Interleukin inhibitors1
Siponimod1230487-00-9Immunosuppressants2
Sirexatamab2414962-49-3Immunomodulators0
Sirolimus53123-88-9Immunosuppressants25
Spermidine124-20-9Immunostimulants3
Tasquinimod254964-60-8Immunomodulators1
Teriflunomide163451-81-8Immunosuppressants25
Thalidomide50-35-1Immunomodulators15
Thymalfasin62304-98-7Immunostimulants9
Timolumab1073538-99-4Immunomodulators0
Tisopurine5334-23-6Immunomodulators0
Tofacitinib477600-75-2Immunosuppressants25
Tositumomab I-131192391-48-3Immunomodulators0
Tranilast53902-12-8Immunosuppressants2
Trastuzumab180288-69-1Monoclonal antibodies7
Tuvirumab138660-97-6Immunomodulators0
Ulenistamab2415259-90-2Immunomodulators0
Urtoxazumab502496-16-4Immunomodulators0
UstekinumabInterleukin inhibitors3
Vedolizumab943609-66-3Immunostimulants1
Vepsitamab2413453-53-7Immunomodulators0
Vixtimotamab2243775-32-6Immunomodulators0
Zamerovimab2419087-87-7Immunomodulators0
Zilovertamab2485779-13-1Immunomodulators0
Zilovertamab vedotin2376463-48-6Immunomodulators0
Zimberelimab2259860-24-5Immunomodulators0