Immunomodulators


Immunomodulators, a category of pharmaceutical active pharmaceutical ingredients (APIs), are substances that help regulate and modify the immune response of an individual. These compounds play a crucial role in treating various immune-related disorders and diseases. Immunomodulators work by either enhancing or suppressing the immune system, depending on the specific condition being treated.

Immunomodulators are used in the treatment of autoimmune disorders, such as rheumatoid arthritis, multiple sclerosis, and psoriasis. By suppressing the immune system, these APIs help reduce the overactive immune response associated with these conditions, thereby alleviating symptoms and preventing further damage to the body's tissues.

On the other hand, immunomodulators are also employed to boost the immune system in cases of immunodeficiency disorders. These APIs stimulate the immune response, enabling the body to better fight off infections and diseases. Additionally, immunomodulators are utilized in the prevention and treatment of organ transplant rejection, where they help modulate the immune system to accept the transplanted organ.

The development and production of immunomodulators require rigorous testing and quality control to ensure their safety and efficacy. Pharmaceutical companies carefully formulate these APIs into various dosage forms, including tablets, capsules, injections, and topical preparations, to cater to different patient needs.

In summary, immunomodulators form a vital category of pharmaceutical APIs that regulate and modify the immune system. With their ability to modulate immune responses, these compounds contribute significantly to the management and treatment of various immune-related disorders and diseases, improving the quality of life for many patients.

NameCAS number
Adenosine monophosphate61-19-8
Aldesleukin110942-02-4
Alpha-1-proteinase inhibitor9041-92-3
Anakinra143090-92-0
Apremilast608141-41-9
Atezolizumab1380723-44-3
Avelumab1537032-82-8
Azathioprine446-86-6
Bevacizumab216974-75-3
Cetuximab205923-56-4
CpG 1018 ODN
CpG 7909 ODN
Cyclosporine59865-13-3
Daratumumab945721-28-8
Dimethyl fumarate624-49-7
Diroximel Fumarate1156109-27-2
Eculizumab219685-50-4
Elafin
Etanercept185243-69-0
Everolimus159351-69-6
Filgotinib maleate1802998-75-9
Fingolimod162359-55-9
Glatiramer Acetate147245-92-9
Imiquimod99011-02-6
Ipilimumab477202-00-9
Leflunomide75706-12-6
Lenalidomide191732-72-6
Lentinan37339-90-5
Mycophenolate mofetil128794-94-5
Mycophenolic acid24280-93-1
Nivolumab946414-94-4
Omalizumab242138-07-4
Pidotimod121808-62-6
Pomalidomide19171-19-8
Ramucirumab947687-13-0
Ravtansine796073-69-3
Rituximab174722-31-7
Secukinumab1229022-83-6
Siltuximab541502-14-1
Siponimod1230487-00-9
Sirolimus53123-88-9
Spermidine124-20-9
Tasquinimod254964-60-8
Teriflunomide163451-81-8
Thalidomide50-35-1
Thymalfasin62304-98-7
Tofacitinib477600-75-2
Tranilast53902-12-8
Trastuzumab180288-69-1
Ustekinumab
Vedolizumab943609-66-3