Normethadone API Manufacturers
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Looking for Normethadone API 467-85-6?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Normethadone. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Normethadone
- Synonyms:
- 6-dimethylamino-4,4-diphenyl-3-hexanone , Desmethylmethadone , Isomethadone I , Normethadone
- Cas Number:
- 467-85-6
- DrugBank number:
- DB11609
- Unique Ingredient Identifier:
- KR2L2A68XL
General Description:
Normethadone, identified by CAS number 467-85-6, is a notable compound with significant therapeutic applications. Normethadone is used as an opioid antitussive in combination with . It is marketed in Canada by Valeant under the tradename Cophylac.
Indications:
This drug is primarily indicated for: For use in the treatment of cough when other less potent treatments have failed . Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Pharmacodynamics:
Normethadone exerts its therapeutic effects through: Normethadone is an opioid which suppresses coughing by central and peripheral mechanisms . The drug's ability to modulate various physiological processes underscores its efficacy in treating specific conditions.
Mechanism of Action:
Normethadone functions by: Normethadone activates central opioid receptors in the medulla to supress the cough reflex . It also likely activates peripheral opioid receptors to inhibit signalling by irritant receptors of the airway. This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Toxicity:
Classification:
Normethadone belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups, classified under the direct parent group Diphenylmethanes. This compound is a part of the Organic compounds, falling under the Benzenoids superclass, and categorized within the Benzene and substituted derivatives class, specifically within the Diphenylmethanes subclass.
Categories:
Normethadone is categorized under the following therapeutic classes: Analgesics, Antitussive Agents, Central Nervous System Agents, Central Nervous System Depressants, Cough and Cold Preparations, Ketones, Narcotics, Opioids, Opium Alkaloids and Derivatives, Peripheral Nervous System Agents, Respiratory System Agents, Sensory System Agents, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Normethadone is a type of Analgesics
Analgesics are a category of pharmaceutical Active Pharmaceutical Ingredients (APIs) that are commonly used to relieve pain. They are designed to alleviate discomfort by targeting the body's pain receptors or by reducing inflammation. Analgesics are widely utilized in the medical field to manage various types of pain, ranging from mild to severe.
One of the primary classes of analgesics is nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs work by inhibiting the production of prostaglandins, substances that contribute to pain and inflammation. This class includes well-known drugs like ibuprofen and naproxen. Another class of analgesics is opioids, which are derived from opium or synthetic compounds that mimic the effects of opium. Opioids act on the central nervous system to reduce pain perception and provide potent pain relief. Examples of opioids include morphine, codeine, and oxycodone.
Analgesics are available in various forms, such as tablets, capsules, creams, and injections, allowing for different routes of administration based on the patient's needs. They are commonly used to manage pain associated with conditions like arthritis, headaches, dental procedures, and post-operative recovery.
It is important to note that analgesics should be used under medical supervision, as improper use or overuse can lead to adverse effects, including gastrointestinal complications, addiction, and respiratory depression in the case of opioids. Therefore, it is crucial for healthcare professionals to assess each patient's individual needs and prescribe the appropriate analgesic and dosage.
In summary, analgesics are a vital category of pharmaceutical APIs used to alleviate pain by targeting pain receptors or reducing inflammation. With various classes and forms available, they provide valuable options for pain management when used responsibly and under medical guidance.
