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Looking for Thonzylamine API 91-85-0?

Description:
Here you will find a list of producers, manufacturers and distributors of Thonzylamine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Thonzylamine 
Synonyms:
neohetramine , Thonzylamine  
Cas Number:
91-85-0 
DrugBank number:
DB11235 
Unique Ingredient Identifier:
R79646H5Z8

General Description:

Thonzylamine, identified by CAS number 91-85-0, is a notable compound with significant therapeutic applications. Thonzylamine is an antihistamine and anticholinergic drug. It is available as combination products with or for temporary relief of symptoms of common cold, hay fever (allergic rhinitis) or other upper respiratory allergies.

Indications:

This drug is primarily indicated for: Thozylamine is indicated for use in the symptomatic control of allergic rhinitis or other upper respiratory allergic symptoms . It is typically a part of combination over the counter products. Its use in specific medical scenarios underscores its importance in the therapeutic landscape.

Pharmacodynamics:

Thonzylamine exerts its therapeutic effects through: Thonzylamine is a first-generation antihistamine. It antagonizes the action of histamine to relief allergic symptoms like nasal congestion, runny nose, itchy eyes, itchy nose and throat, and sneezing. The drug's ability to modulate various physiological processes underscores its efficacy in treating specific conditions.

Mechanism of Action:

Thonzylamine functions by: Thonzylamine competes with histamine for binding to the H1 histamine receptor . Binding of histamine to this receptor stimulates vasodilation and increased vascular permeability leading to nasal congestion and runny nose . Histamine also produces itchiness by stimulating nerve endings which can result in sneezing. By blocking these effects, thonzylamine can reduce or eliminate symptoms of allergic rhinitis. This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.

Toxicity:

Classification:

Thonzylamine belongs to the class of organic compounds known as anisoles. These are organic compounds containing a methoxybenzene or a derivative thereof, classified under the direct parent group Anisoles. This compound is a part of the Organic compounds, falling under the Benzenoids superclass, and categorized within the Phenol ethers class, specifically within the Anisoles subclass.

Categories:

Thonzylamine is categorized under the following therapeutic classes: Agents producing tachycardia, Antiallergic Agents, Excl. Corticosteroids, Anticholinergic Agents, Antihistamines for Systemic Use, Antihistamines for Topical Use, Antipruritics, Incl. Antihistamines, Anesthetics, Etc, Dermatologicals, Histamine Agents, Histamine Antagonists, Histamine H1 Antagonists, Muscarinic Antagonists, Nasal Preparations, Neurotransmitter Agents, Substituted Ethylene Diamines. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.

Experimental Properties:

Further physical and chemical characteristics of Thonzylamine include:

  • Water Solubility: Highly Soluble
  • Melting Point: 173-176

Thonzylamine is a type of Anesthetics


Anesthetics are a crucial category of pharmaceutical Active Pharmaceutical Ingredients (APIs) widely used in the field of medicine. These substances play a vital role in inducing a temporary loss of sensation or consciousness, enabling medical procedures to be performed without pain or discomfort. Anesthetics can be classified into two primary types: general anesthetics and local anesthetics.

General anesthetics act on the central nervous system, producing a reversible loss of consciousness. They are administered through inhalation or injection routes and are commonly employed for major surgeries or procedures that require deep sedation. Examples of general anesthetics include sevoflurane, propofol, and isoflurane.

On the other hand, local anesthetics primarily target a specific region or part of the body, temporarily numbing the area and blocking pain signals. These APIs are frequently used in dental procedures, minor surgeries, and childbirth. Common local anesthetics include lidocaine, bupivacaine, and ropivacaine.

Anesthetics work by interfering with the transmission of nerve signals or by altering the activity of certain receptors in the nervous system. They offer precise control over pain management, allowing medical professionals to perform complex procedures with reduced patient discomfort and anxiety.

The development and manufacturing of anesthetics APIs require stringent quality control measures to ensure safety and efficacy. Pharmaceutical companies adhere to strict regulatory guidelines to produce high-quality APIs. The demand for anesthetics remains consistently high, making this category of APIs a critical component of the pharmaceutical industry.

In conclusion, anesthetics are indispensable pharmaceutical APIs used to induce temporary loss of sensation or consciousness. They can be classified into general and local anesthetics, each serving distinct purposes in medical procedures. The proper development and manufacturing of anesthetics APIs are essential to ensure safe and effective pain management in various healthcare settings.