Dapivirine API Manufacturers

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Looking for Dapivirine API 244767-67-7?

Description:
Here you will find a list of producers, manufacturers and distributors of Dapivirine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Dapivirine 
Synonyms:
 
Cas Number:
244767-67-7 
DrugBank number:
DB08639 
Unique Ingredient Identifier:
TCN4MG2VXS

General Description:

Dapivirine, identified by CAS number 244767-67-7, is a notable compound with significant therapeutic applications. Dapivirine has been investigated for the prevention of HIV-1 Infections and Topical Penile Exposures.

Classification:

Dapivirine belongs to the class of organic compounds known as benzonitriles. These are organic compounds containing a benzene bearing a nitrile substituent, classified under the direct parent group Benzonitriles. This compound is a part of the Organic compounds, falling under the Benzenoids superclass, and categorized within the Benzene and substituted derivatives class, specifically within the Benzonitriles subclass.

Categories:

Dapivirine is categorized under the following therapeutic classes: Anti-HIV Agents, Anti-Infective Agents, Anti-Retroviral Agents, Antiviral Agents, Genito Urinary System and Sex Hormones, Gynecological Antiinfectives and Antiseptics, HIV Reverse Transcriptase. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.

Dapivirine is a type of Anti-HIV


The Anti-HIV category of pharmaceutical APIs comprises a range of active pharmaceutical ingredients (APIs) specifically designed to combat the human immunodeficiency virus (HIV). These APIs play a critical role in the development and production of antiretroviral drugs, which are used to treat HIV infections and prevent the progression to acquired immunodeficiency syndrome (AIDS).

Anti-HIV APIs work by targeting various stages of the HIV life cycle, inhibiting viral replication and reducing the viral load in the body. Some commonly used APIs in this category include nucleoside reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), protease inhibitors (PIs), and integrase inhibitors (INIs).

NRTIs, such as tenofovir and emtricitabine, act by blocking the reverse transcriptase enzyme, an essential component in the replication of the virus. NNRTIs, such as efavirenz and nevirapine, bind to the reverse transcriptase enzyme, preventing its proper functioning. PIs, like ritonavir and atazanavir, inhibit the protease enzyme, crucial for viral maturation and assembly. INIs, such as raltegravir and dolutegravir, target the integrase enzyme, impeding viral integration into the host's DNA.

These APIs are carefully synthesized and undergo rigorous quality testing to ensure their safety, efficacy, and compliance with regulatory standards. Pharmaceutical companies utilize these APIs as key building blocks to formulate antiretroviral medications, which are then prescribed to individuals living with HIV/AIDS worldwide.

Overall, the Anti-HIV API category plays a vital role in the ongoing battle against HIV/AIDS, offering effective treatment options and improved quality of life for patients affected by this challenging condition.