Hypochlorite API Manufacturers

General Description:

Hypochlorite, identified by CAS number 14380-61-1, is a notable compound with significant therapeutic applications. Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and water treatment purposes in its salt form, sodium hypochlorite. Hypochlorite is often used as a chemical reagent for chlorination and oxidation reactions.

Indications:

This drug is primarily indicated for: Indicated for over-the-counter use as a disinfectant agent in the sodium hypochlorite form. Its use in specific medical scenarios underscores its importance in the therapeutic landscape.

Metabolism:

Hypochlorite undergoes metabolic processing primarily in: This pharmacokinetic parameter does not apply for this drug. Hypochlorite salts are expected to undergo dissociation. This metabolic pathway ensures efficient processing of the drug, helping to minimize potential toxicity and side effects.

Absorption:

The absorption characteristics of Hypochlorite are crucial for its therapeutic efficacy: This pharmacokinetic parameter does not apply for this drug. The drug's ability to rapidly penetrate into cells ensures quick onset of action.

Half-life:

The half-life of Hypochlorite is an important consideration for its dosing schedule: This pharmacokinetic parameter does not apply for this drug. This determines the duration of action and helps in formulating effective dosing regimens.

Protein Binding:

Hypochlorite exhibits a strong affinity for binding with plasma proteins: This pharmacokinetic parameter does not apply for this drug. This property plays a key role in the drug's pharmacokinetics and distribution within the body.

Route of Elimination:

The elimination of Hypochlorite from the body primarily occurs through: This pharmacokinetic parameter does not apply for this drug. Understanding this pathway is essential for assessing potential drug accumulation and toxicity risks.

Volume of Distribution:

Hypochlorite is distributed throughout the body with a volume of distribution of: This pharmacokinetic parameter does not apply for this drug. This metric indicates how extensively the drug permeates into body tissues.

Clearance:

The clearance rate of Hypochlorite is a critical factor in determining its safe and effective dosage: This pharmacokinetic parameter does not apply for this drug. It reflects the efficiency with which the drug is removed from the systemic circulation.

Pharmacodynamics:

Hypochlorite exerts its therapeutic effects through: Sodium hypochlorite exerts antimicrobial actions that depends on the concentration of the available chlorine and the pH of the solution . The concentration of the hypochlorite depends on the overall efficiency of disinfection . The drug's ability to modulate various physiological processes underscores its efficacy in treating specific conditions.

Mechanism of Action:

Hypochlorite functions by: Sodium hypochlorite mediate its antimicrobial action by reacting with fatty acids and amino acids. Via saponification reaction, it acts as an organic and fat solvent, degrading fatty acids to form fatty acids and glycerol . This reduces the surface tension of the remaining solution. Sodium hypochlorite may react with amino acids to neutralize them and form water and salt. Hypochlorous acids (HOCl-) present in sodium hypochlorite solutions may act as solvents in contact with organic tissue to release chlorine, which forms chloramines when combined with the protein amino group that disrupt cell metabolism . Chlorine in the solution is a strong oxidant that inhibits essential bacterial enzymes leading to an irreversible oxidation of SH groups . Eventually hypochlorous acid and hypochlorite ions degrade and hydrolyze amino acids. This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.

Toxicity:

Classification:

Hypochlorite belongs to the class of inorganic compounds known as non-metal hypochlorites. These are inorganic non-metallic compounds containing a hypochlorite as its largest oxoanion, classified under the direct parent group Non-metal hypochlorites. This compound is a part of the Inorganic compounds, falling under the Homogeneous non-metal compounds superclass, and categorized within the Non-metal oxoanionic compounds class, specifically within the Non-metal hypochlorites subclass.

Categories:

Hypochlorite is categorized under the following therapeutic classes: Acids, Acids, Noncarboxylic, Anti-Infective Agents, Antiseptics and Disinfectants, Chlorine Compounds, Compounds used in a research, industrial, or household setting, Dermatologicals, Disinfectants, Free Radicals, Miscellaneous Local Anti-infectives, Noxae, Oxidants, Oxides, Oxygen Compounds, Reactive Oxygen Species, Sodium Compounds, Toxic Actions. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.

Experimental Properties:

Further physical and chemical characteristics of Hypochlorite include:

• Water Solubility: Soluble (sodium hypochlorite)
• Boiling Point: Decomposes at 40 (sodium hypochlorite)