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Oxyquinoline
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Looking for Oxyquinoline API 148-24-3?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Oxyquinoline. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Oxyquinoline
- Synonyms:
- 8-Hydroxyquinoline , hydroxybenzopyridine , Hydroxyquinoline , oxine , Phenopyridine
- Cas Number:
- 148-24-3
- DrugBank number:
- DB11145
- Unique Ingredient Identifier:
- 5UTX5635HP
General Description:
Oxyquinoline, identified by CAS number 148-24-3, is a notable compound with significant therapeutic applications. Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products.
Indications:
This drug is primarily indicated for: Oxyquinoline is used as a biocidal component of several over the counter products. These products are marketed for the purposes of inhibiting abnormal biological growth in the vagina and restoring natural pH. Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Metabolism:
Oxyquinoline undergoes metabolic processing primarily in: In the urine, 60% of the dose is excreted as glucuronide conjugates and 23% of the dose as sulfate conjugates . In the bile, 9% of the total dose is found as glucuronide conjugates. This metabolic pathway ensures efficient processing of the drug, helping to minimize potential toxicity and side effects.
Route of Elimination:
The elimination of Oxyquinoline from the body primarily occurs through: Oxyquinoline is excreted in both the primarily in the urine with some in the bile . Understanding this pathway is essential for assessing potential drug accumulation and toxicity risks.
Pharmacodynamics:
Oxyquinoline exerts its therapeutic effects through: Oxyquinoline acts as a biocide to eliminate bacteria and fungi . The drug's ability to modulate various physiological processes underscores its efficacy in treating specific conditions.
Mechanism of Action:
Oxyquinoline functions by: The mechanism by which oxyquinoline exerts its biocidal effect is unknown. This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Classification:
Oxyquinoline belongs to the class of organic compounds known as 8-hydroxyquinolines. These are compounds containing a quinoline moiety, which carries a hydroxy group at the 8-position. Quinoline consists of a benzene ring fused to a pyrimidine ring to form benzo[b]azabenzene, classified under the direct parent group 8-hydroxyquinolines. This compound is a part of the Organic compounds, falling under the Organoheterocyclic compounds superclass, and categorized within the Quinolines and derivatives class, specifically within the 8-hydroxyquinolines subclass.
Categories:
Oxyquinoline is categorized under the following therapeutic classes: Alimentary Tract and Metabolism, Anti-Infective Agents, Local, Antiinfectives and Antiseptics for Local Oral Treatment, Antiseptics and Disinfectants, Dermatologicals, Drugs that are Mainly Renally Excreted, Genito Urinary System and Sex Hormones, Gynecological Antiinfectives and Antiseptics, Heterocyclic Compounds, Fused-Ring, Hydroxyquinolines, Quinoline Derivatives, Quinolines, Stomatological Preparations, Throat Preparations. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Experimental Properties:
Further physical and chemical characteristics of Oxyquinoline include:
- Water Solubility: Insoluble
- Melting Point: 76
- Boiling Point: 267
- pKa: 5.017
Oxyquinoline is a type of Anti-infective Agents
Anti-infective agents are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used in the treatment of various infectious diseases. These agents play a crucial role in combating bacterial, viral, fungal, and parasitic infections. The demand for effective anti-infective APIs has grown significantly due to the increasing prevalence of drug-resistant microorganisms.
Anti-infective APIs encompass a wide range of substances, including antibiotics, antivirals, antifungals, and antiparasitics. Antibiotics are particularly important in fighting bacterial infections and are further categorized into different classes based on their mode of action and target bacteria. Antivirals are designed to inhibit viral replication and are essential in the treatment of viral infections such as influenza and HIV. Antifungals combat fungal infections, while antiparasitics are used to eliminate parasites that cause diseases like malaria and helminthiasis.
The development and production of high-quality anti-infective APIs require stringent manufacturing processes and adherence to regulatory standards. Pharmaceutical companies invest heavily in research and development to discover new and more effective anti-infective agents. Additionally, ensuring the safety, efficacy, and stability of these APIs is of utmost importance.
The global market for anti-infective APIs is driven by factors such as the rising incidence of infectious diseases, the emergence of new and drug-resistant pathogens, and the growing demand for improved healthcare infrastructure. Continuous advancements in pharmaceutical technology and the development of innovative drug delivery systems further contribute to the expansion of this market.
In conclusion, anti-infective agents are a critical category of pharmaceutical APIs that play a pivotal role in treating infectious diseases. Their effectiveness in combating various types of infections makes them essential components in the arsenal of modern medicine.
