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Parachlorophenol
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Looking for Parachlorophenol API 106-48-9?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Parachlorophenol. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Parachlorophenol
- Synonyms:
- 4-Chlorophenol , 4-chlorphenol , p-Chlorophenol , Parachlorophenol
- Cas Number:
- 106-48-9
- DrugBank number:
- DB13154
- Unique Ingredient Identifier:
- 3DLC36A01X
General Description:
Parachlorophenol, identified by CAS number 106-48-9, is a notable compound with significant therapeutic applications. P-chlorophenol is a white crystals with a strong phenol odor. Slightly soluble to soluble in water, depending on the isomer, and denser than water. Noncombustible.
Indications:
This drug is primarily indicated for: Used as an intermediate in organic synthesis of dyes and drugs. Local antibacterial agent in root canal therapy, as topical antiseptic in ointments. Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Metabolism:
Parachlorophenol undergoes metabolic processing primarily in: P-Chlorophenol yields p-chloroanisole in guinea pigs. P-Chlorophenol yields 4-chlorocatechol p-chloro phenyl-beta-D-glucuronide & p-chlorphenyl sulfate in rabbits. P-Chlorophenol yields p-chlorophenyl sulfate in rats. This metabolic pathway ensures efficient processing of the drug, helping to minimize potential toxicity and side effects.
Absorption:
The absorption characteristics of Parachlorophenol are crucial for its therapeutic efficacy: absorbed from gastrointestinal tract. The drug's ability to rapidly penetrate into cells ensures quick onset of action.
Route of Elimination:
The elimination of Parachlorophenol from the body primarily occurs through: 87% of 4-chlorophenol was excreted in urine of dogs as sulfate and glucuronide. Understanding this pathway is essential for assessing potential drug accumulation and toxicity risks.
Mechanism of Action:
Parachlorophenol functions by: The major mode of action of chlorophenols appears to be the uncoupling of oxidative phosphorylation. The strength of the uncoupling effect is related to the degree of chlorination: PCP is the strongest inhibitor of oxidative phosphorylation, MCP the weakest. To a lesser extent, inhibition of oxidative phosphorylation is affected by the positions of the chlorine atoms on the molecule. This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Toxicity:
Classification:
Parachlorophenol belongs to the class of organic compounds known as p-chlorophenols. These are chlorophenols carrying a iodine at the C4 position of the benzene ring, classified under the direct parent group P-chlorophenols. This compound is a part of the Organic compounds, falling under the Benzenoids superclass, and categorized within the Phenols class, specifically within the Halophenols subclass.
Categories:
Parachlorophenol is categorized under the following therapeutic classes: Anti-Infective Agents, Anti-Infective Agents, Local, Benzene Derivatives, Chlorobenzenes, Drugs that are Mainly Renally Excreted, OATP1B3 substrates, Phenols. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Parachlorophenol is a type of Anti-infective Agents
Anti-infective agents are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used in the treatment of various infectious diseases. These agents play a crucial role in combating bacterial, viral, fungal, and parasitic infections. The demand for effective anti-infective APIs has grown significantly due to the increasing prevalence of drug-resistant microorganisms.
Anti-infective APIs encompass a wide range of substances, including antibiotics, antivirals, antifungals, and antiparasitics. Antibiotics are particularly important in fighting bacterial infections and are further categorized into different classes based on their mode of action and target bacteria. Antivirals are designed to inhibit viral replication and are essential in the treatment of viral infections such as influenza and HIV. Antifungals combat fungal infections, while antiparasitics are used to eliminate parasites that cause diseases like malaria and helminthiasis.
The development and production of high-quality anti-infective APIs require stringent manufacturing processes and adherence to regulatory standards. Pharmaceutical companies invest heavily in research and development to discover new and more effective anti-infective agents. Additionally, ensuring the safety, efficacy, and stability of these APIs is of utmost importance.
The global market for anti-infective APIs is driven by factors such as the rising incidence of infectious diseases, the emergence of new and drug-resistant pathogens, and the growing demand for improved healthcare infrastructure. Continuous advancements in pharmaceutical technology and the development of innovative drug delivery systems further contribute to the expansion of this market.
In conclusion, anti-infective agents are a critical category of pharmaceutical APIs that play a pivotal role in treating infectious diseases. Their effectiveness in combating various types of infections makes them essential components in the arsenal of modern medicine.
