Bergapten API Manufacturers
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Looking for Bergapten API 484-20-8?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Bergapten. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Bergapten
- Synonyms:
- 5 methoxypsoralen , 5-methoxypsoralen
- Cas Number:
- 484-20-8
- DrugBank number:
- DB12216
- Unique Ingredient Identifier:
- 4FVK84C92X
General Description:
Bergapten, identified by CAS number 484-20-8, is a notable compound with significant therapeutic applications. Bergapten is under investigation in clinical trial NCT00533195 (Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis).
Classification:
Bergapten belongs to the class of organic compounds known as 5-methoxypsoralens. These are psoralens containing a methoxy group attached at the C5 position of the psoralen group, classified under the direct parent group 5-methoxypsoralens. This compound is a part of the Organic compounds, falling under the Phenylpropanoids and polyketides superclass, and categorized within the Coumarins and derivatives class, specifically within the Furanocoumarins subclass.
Categories:
Bergapten is categorized under the following therapeutic classes: Anti-Inflammatory Agents, Antipsoriatics, Antipsoriatics for Systemic Use, Benzopyrans, Coumarins, Dermatologicals, Furocoumarins, Heterocyclic Compounds, Fused-Ring, Photosensitizing Agents, Photosensitizing Agents for Phototherapy, Psoralens for Systemic Use, Pyrans, Radiation-Sensitizing Agents. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Bergapten is a type of Anti-inflammatory Agents
Anti-inflammatory agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat various inflammatory conditions. These agents play a vital role in alleviating pain, reducing swelling, and controlling inflammation in the body. They are widely employed in the management of diverse medical conditions, including arthritis, autoimmune disorders, asthma, and skin conditions like dermatitis.
Anti-inflammatory APIs primarily function by inhibiting the production of specific enzymes called cyclooxygenases (COX) and lipoxygenases (LOX). These enzymes are responsible for the synthesis of pro-inflammatory molecules known as prostaglandins and leukotrienes, respectively. By suppressing the activity of COX and LOX, anti-inflammatory agents effectively curtail the production of these inflammatory mediators, thereby mitigating inflammation.
Common examples of anti-inflammatory APIs include non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, aspirin, and naproxen. These agents exhibit analgesic, antipyretic, and anti-inflammatory properties. Another group of anti-inflammatory APIs includes corticosteroids, such as prednisone and dexamethasone, which are synthetic hormones that modulate the body's immune response to control inflammation.
In conclusion, anti-inflammatory agents are a vital category of pharmaceutical APIs widely used to manage inflammation-related disorders. They target enzymes involved in the synthesis of pro-inflammatory molecules, effectively reducing pain and swelling. NSAIDs and corticosteroids are commonly prescribed anti-inflammatory APIs due to their efficacy in controlling inflammation.
