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Polydatin
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Looking for Polydatin API 27208-80-6?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Polydatin. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Polydatin
- Synonyms:
- 3,4,5-Trihydroxystilbene-3-beta-monoglucoside , 3,4',5-trihydroxystilbene-3-β-d-glucoside , Piceid , Polydatin (E)-isomer , Resveratrol 3-O-beta-glucopyranoside , resveratrol-3-O-b-mono-D-glucoside , trans-piceid , trans-resveratrol 3-O-β-D-glucoside , trans-resveratrol 3-β-D-glucoside , trans-resveratrol 3-β-glucoside
- Cas Number:
- 27208-80-6
- DrugBank number:
- DB11263
- Unique Ingredient Identifier:
- XM261C37CQ
General Description:
Polydatin, identified by CAS number 27208-80-6, is a notable compound with significant therapeutic applications. Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of *Picea sitchensis* or *Polygonum cuspidatum*, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets . Polydatin possesses anti-inflammatory, immunoregulatory, anti-oxidative and anti-tumor activities. It is shown to mediate a cytotoxic action on colorectal cancer cells by inducing cell arrest and apoptosis .
Classification:
Polydatin belongs to the class of organic compounds known as stilbene glycosides. These are compounds structurally characterized by the presence of a carbohydrate moiety glycosidically linked to the stilbene skeleton, classified under the direct parent group Stilbene glycosides. This compound is a part of the Organic compounds, falling under the Phenylpropanoids and polyketides superclass, and categorized within the Stilbenes class, specifically within the Stilbene glycosides subclass.
Categories:
Polydatin is categorized under the following therapeutic classes: Benzene Derivatives, Benzylidene Compounds, Carbohydrates, Drugs, Chinese Herbal, Glycosides, Plant Extracts. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Polydatin is a type of Anti-inflammatory Agents
Anti-inflammatory agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat various inflammatory conditions. These agents play a vital role in alleviating pain, reducing swelling, and controlling inflammation in the body. They are widely employed in the management of diverse medical conditions, including arthritis, autoimmune disorders, asthma, and skin conditions like dermatitis.
Anti-inflammatory APIs primarily function by inhibiting the production of specific enzymes called cyclooxygenases (COX) and lipoxygenases (LOX). These enzymes are responsible for the synthesis of pro-inflammatory molecules known as prostaglandins and leukotrienes, respectively. By suppressing the activity of COX and LOX, anti-inflammatory agents effectively curtail the production of these inflammatory mediators, thereby mitigating inflammation.
Common examples of anti-inflammatory APIs include non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, aspirin, and naproxen. These agents exhibit analgesic, antipyretic, and anti-inflammatory properties. Another group of anti-inflammatory APIs includes corticosteroids, such as prednisone and dexamethasone, which are synthetic hormones that modulate the body's immune response to control inflammation.
In conclusion, anti-inflammatory agents are a vital category of pharmaceutical APIs widely used to manage inflammation-related disorders. They target enzymes involved in the synthesis of pro-inflammatory molecules, effectively reducing pain and swelling. NSAIDs and corticosteroids are commonly prescribed anti-inflammatory APIs due to their efficacy in controlling inflammation.
