Tetrahydropalmatine API Manufacturers
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Looking for Tetrahydropalmatine API 483-14-7?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Tetrahydropalmatine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Tetrahydropalmatine
- Synonyms:
- Cas Number:
- 483-14-7
- DrugBank number:
- DB12093
- Unique Ingredient Identifier:
- 3X69CO5I79
General Description:
Tetrahydropalmatine, identified by CAS number 483-14-7, is a notable compound with significant therapeutic applications. Tetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).
Classification:
Tetrahydropalmatine belongs to the class of organic compounds known as protoberberine alkaloids and derivatives. These are alkaloids with a structure based on a protoberberine moiety, which consists of a 5,6-dihydrodibenzene moiety fused to a quinolizinium and forming 5,6-Dihydrodibenzo(a,g)quinolizinium skeleton, classified under the direct parent group Protoberberine alkaloids and derivatives. This compound is a part of the Organic compounds, falling under the Alkaloids and derivatives superclass, and categorized within the Protoberberine alkaloids and derivatives class, specifically within the None subclass.
Categories:
Tetrahydropalmatine is categorized under the following therapeutic classes: Adrenergic Agents, Agents causing hyperkalemia, Alkaloids, Analgesics, Analgesics, Non-Narcotic, Antiarrhythmic agents, Antihypertensive Agents, Antipsychotic Agents, Benzylisoquinolines, Bradycardia-Causing Agents, Calcium Channel Blockers, Calcium-Regulating Hormones and Agents, Cardiovascular Agents, Central Nervous System Agents, Central Nervous System Depressants, Cytochrome P-450 CYP3A Substrates, Cytochrome P-450 CYP3A4 Substrates, Cytochrome P-450 Substrates, Dopamine Agents, Dopamine Antagonists, Dopamine D2 Receptor Antagonists, Heterocyclic Compounds, Fused-Ring, Membrane Transport Modulators, Neurotoxic agents, Neurotransmitter Agents, Peripheral Nervous System Agents, Potential QTc-Prolonging Agents, Psychotropic Drugs, QTc Prolonging Agents, Sensory System Agents, Tranquilizing Agents, Vasodilating Agents. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Tetrahydropalmatine is a type of Anti-inflammatory Agents
Anti-inflammatory agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat various inflammatory conditions. These agents play a vital role in alleviating pain, reducing swelling, and controlling inflammation in the body. They are widely employed in the management of diverse medical conditions, including arthritis, autoimmune disorders, asthma, and skin conditions like dermatitis.
Anti-inflammatory APIs primarily function by inhibiting the production of specific enzymes called cyclooxygenases (COX) and lipoxygenases (LOX). These enzymes are responsible for the synthesis of pro-inflammatory molecules known as prostaglandins and leukotrienes, respectively. By suppressing the activity of COX and LOX, anti-inflammatory agents effectively curtail the production of these inflammatory mediators, thereby mitigating inflammation.
Common examples of anti-inflammatory APIs include non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, aspirin, and naproxen. These agents exhibit analgesic, antipyretic, and anti-inflammatory properties. Another group of anti-inflammatory APIs includes corticosteroids, such as prednisone and dexamethasone, which are synthetic hormones that modulate the body's immune response to control inflammation.
In conclusion, anti-inflammatory agents are a vital category of pharmaceutical APIs widely used to manage inflammation-related disorders. They target enzymes involved in the synthesis of pro-inflammatory molecules, effectively reducing pain and swelling. NSAIDs and corticosteroids are commonly prescribed anti-inflammatory APIs due to their efficacy in controlling inflammation.
