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Diosmetin API Manufacturers & Suppliers

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Looking for Diosmetin API 520-34-3?

Description:
Here you will find a list of producers, manufacturers and distributors of Diosmetin. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Diosmetin 
Synonyms:
3',5,7-trihydroxy-4'-methoxyflavone , 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone , Luteolin 4'-methyl ether , Salinigricoflavonol  
Cas Number:
520-34-3 
DrugBank number:
DB11259 
Unique Ingredient Identifier:
TWZ37241OT

General Description:

Diosmetin, identified by CAS number 520-34-3, is a notable compound with significant therapeutic applications. Diosmetin is an O-methylated flavone and the aglycone part of the flavonoid glycosides diosmin that occurs naturally in citrus fruits . Pharmacologically, diosmetin is reported to exhibit anticancer, antimicrobial, antioxidant, oestrogenic and anti-inflamatory activities . It also acts as a weak TrkB receptor agonist .

Absorption:

The absorption characteristics of Diosmetin are crucial for its therapeutic efficacy: Diosmin is hydrolyzed to its aglycone diosmetin by intestinal microflora enzymes before its absorption into the body . The drug's ability to rapidly penetrate into cells ensures quick onset of action.

Classification:

Diosmetin belongs to the class of organic compounds known as 4'-o-methylated flavonoids. These are flavonoids with methoxy groups attached to the C4' atom of the flavonoid backbone, classified under the direct parent group 4'-O-methylated flavonoids. This compound is a part of the Organic compounds, falling under the Phenylpropanoids and polyketides superclass, and categorized within the Flavonoids class, specifically within the O-methylated flavonoids subclass.

Categories:

Diosmetin is categorized under the following therapeutic classes: Benzopyrans, Chromones, Heterocyclic Compounds, Fused-Ring, Pyrans. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.

Diosmetin is a type of Anticancer drugs


Anticancer drugs belong to the pharmaceutical API (Active Pharmaceutical Ingredient) category designed specifically to combat cancer cells. These powerful medications play a crucial role in cancer treatment and are developed to target and destroy cancerous cells, preventing their growth and spread.

Anticancer drugs are classified based on their mode of action and can include various types such as chemotherapy drugs, targeted therapy drugs, immunotherapy drugs, and hormonal therapy drugs. Chemotherapy drugs work by interfering with the cell division process, thereby inhibiting the growth of cancer cells. Targeted therapy drugs, on the other hand, are designed to attack specific molecules or genes involved in cancer growth, minimizing damage to healthy cells. Immunotherapy drugs stimulate the body's immune system to recognize and destroy cancer cells. Hormonal therapy drugs are used in cancers that are hormone-dependent, such as breast or prostate cancer, to block the hormones that fuel cancer cell growth.

These APIs are typically synthesized through complex chemical processes in state-of-the-art manufacturing facilities. Stringent quality control measures ensure the purity, potency, and safety of these drugs. Anticancer APIs undergo rigorous testing and adhere to stringent regulatory guidelines before being approved for clinical use.

Due to their critical role in cancer treatment, anticancer drugs are in high demand worldwide. Researchers and pharmaceutical companies continually strive to develop new and more effective APIs in this category to enhance treatment outcomes and minimize side effects. The ongoing advancements in the field of anticancer drug development offer hope for improved cancer therapies and better patient outcomes.