Neon API Manufacturers

General Description:

Neon, identified by CAS number 7440-01-9, is a notable compound with significant therapeutic applications. Neon is a chemical element with a chemical symbol Ne and atomic number 10. It is a noble gas that is colorless, odorless, inert and monatomic. It is the fifth most abundant chemical element in the universe by mass but a rare element on Earth. It displays a reddish-orange light, and is commonly used in low-voltage neon glow lamps, high-voltage discharge tubes, and signs with fluorescent lighting. It is also used in vacuum tubes, high-voltage indicators, lightning arresters, wave meter tubes, television tubes, and helium–neon lasers. Neon may be used in the clinical setting as a diagnostic tracer gas in a gas analyzer for a lung diffusion test. Other clinical applications of neon, such as a radiotherapy in various cancers , have been studied.

Indications:

This drug is primarily indicated for: Indicated for use as a diagnostic tracer gas in pulmonary function tests. Its use in specific medical scenarios underscores its importance in the therapeutic landscape.

Metabolism:

Neon undergoes metabolic processing primarily in: No pharmacokinetic data available. This metabolic pathway ensures efficient processing of the drug, helping to minimize potential toxicity and side effects.

Absorption:

The absorption characteristics of Neon are crucial for its therapeutic efficacy: No pharmacokinetic data available. The drug's ability to rapidly penetrate into cells ensures quick onset of action.

Half-life:

The half-life of Neon is an important consideration for its dosing schedule: No pharmacokinetic data available. This determines the duration of action and helps in formulating effective dosing regimens.

Protein Binding:

Neon exhibits a strong affinity for binding with plasma proteins: No pharmacokinetic data available. This property plays a key role in the drug's pharmacokinetics and distribution within the body.

Route of Elimination:

The elimination of Neon from the body primarily occurs through: No pharmacokinetic data available. Understanding this pathway is essential for assessing potential drug accumulation and toxicity risks.

Volume of Distribution:

Neon is distributed throughout the body with a volume of distribution of: No pharmacokinetic data available. This metric indicates how extensively the drug permeates into body tissues.

Clearance:

The clearance rate of Neon is a critical factor in determining its safe and effective dosage: No pharmacokinetic data available. It reflects the efficiency with which the drug is removed from the systemic circulation.

Pharmacodynamics:

Neon exerts its therapeutic effects through: A study demonstrated that neon beam radiotherapy improved the 5-year actuarial disease-specific survival rate and local control in patients with paranasal sinus tumours, macroscopic salivary gland tumours, bile duct carcinomas, macroscopic soft tissue and bone sarcomas, and advanced prostate carcinomas . The drug's ability to modulate various physiological processes underscores its efficacy in treating specific conditions.

Mechanism of Action:

Neon functions by: In a pulmonary diffusion capacity test, the diffusing capacity for carbon monoxide (Dlco) assesses the rate at which oxygen is transferred from the lung to the pulmonary capillary bed. In a neon gas analyzer, the mixture of carbon monoxide, neon gas, oxygen, and the balance nitrogen is inhaled by the individual and is eventually exhaled after being held at near full inspiration for brief seconds. The concentrations and ratio of carbon monoxide and neon is measured in the alveolar fraction of the expired gas. The change in the concentration of the tracer gas reflects the mean alveolar carbon monoxide concentration at the start of the breath hold and provides a measure of alveolar volume by gas dilution . Neon ion radiotherapy has high linear energy transfer thus produces biological behaviour similar to neutron beams . The rays are associated with a reduction in the oxygen enhancement ratio, which allows for more specificity for hypoxic cells, less variation in cell-cycle related radio sensitivity, and less capability for repair of radiation injury . This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.

Toxicity:

Classification:

Neon belongs to the class of inorganic compounds known as homogeneous noble gases. These are inorganic non-metallic compounds in which the largest atom is a halogen atom, classified under the direct parent group Homogeneous noble gases. This compound is a part of the Inorganic compounds, falling under the Homogeneous non-metal compounds superclass, and categorized within the Homogeneous noble gases class, specifically within the None subclass.

Categories:

Neon is categorized under the following therapeutic classes: Elements, Gases, Noble Gases. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.

Experimental Properties:

Further physical and chemical characteristics of Neon include:

• Water Solubility: Negligible
• Melting Point: -248.7
• Boiling Point: -246.1