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Palifosfamide
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Looking for Palifosfamide API 31645-39-3?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Palifosfamide. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Palifosfamide
- Synonyms:
- Ifosfamide mustard , Ifosforamide mustard , Isophosphamide mustard , Isophosphoramide mustard , Palifosfamide
- Cas Number:
- 31645-39-3
- DrugBank number:
- DB05668
- Unique Ingredient Identifier:
- 6A4U6NN813
General Description:
Palifosfamide, identified by CAS number 31645-39-3, is a notable compound with significant therapeutic applications. Palifosfamide (ZIO-201) is a proprietary stabilized metabolite of ifosfamide. Ifosfamide has been shown to be effective in high doses in treating testicular cancer, sarcoma and lymphoma.
Indications:
This drug is primarily indicated for: Investigated for use/treatment in cancer/tumors (unspecified), lymphoma (unspecified), and sarcoma. Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Mechanism of Action:
Palifosfamide functions by: After metabolic activation, palifosfamide alkylates or binds with many intracellular molecular structures, including nucleic acids. The cytotoxic action is primarily due to cross-linking of strands of DNA and RNA, as well as inhibition of protein synthesis. This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Classification:
Palifosfamide belongs to the class of organic compounds known as organic phosphoric acid diamides. These are organophosphorus compounds with the general formula RNP(R2)(O)=O (R=alkyl, aryl; R2 = amine group), classified under the direct parent group Organic phosphoric acid diamides. This compound is a part of the Organic compounds, falling under the Organic acids and derivatives superclass, and categorized within the Organic phosphoric acids and derivatives class, specifically within the Organic phosphoramides subclass.
Categories:
Palifosfamide is categorized under the following therapeutic classes: Alkylating Drugs, Amino Acids, Amino Acids, Basic, Amino Acids, Diamino, Amino Acids, Peptides, and Proteins, Antineoplastic Agents, Antineoplastic Agents, Alkylating, Hydrocarbons, Halogenated, Mustard Compounds, Nitrogen Mustard Compounds, Noxae, Organophosphorus Compounds, Oxazines, Phosphoramide Mustards, Phosphoramides, Toxic Actions. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Palifosfamide is a type of Anticancer drugs
Anticancer drugs belong to the pharmaceutical API (Active Pharmaceutical Ingredient) category designed specifically to combat cancer cells. These powerful medications play a crucial role in cancer treatment and are developed to target and destroy cancerous cells, preventing their growth and spread.
Anticancer drugs are classified based on their mode of action and can include various types such as chemotherapy drugs, targeted therapy drugs, immunotherapy drugs, and hormonal therapy drugs. Chemotherapy drugs work by interfering with the cell division process, thereby inhibiting the growth of cancer cells. Targeted therapy drugs, on the other hand, are designed to attack specific molecules or genes involved in cancer growth, minimizing damage to healthy cells. Immunotherapy drugs stimulate the body's immune system to recognize and destroy cancer cells. Hormonal therapy drugs are used in cancers that are hormone-dependent, such as breast or prostate cancer, to block the hormones that fuel cancer cell growth.
These APIs are typically synthesized through complex chemical processes in state-of-the-art manufacturing facilities. Stringent quality control measures ensure the purity, potency, and safety of these drugs. Anticancer APIs undergo rigorous testing and adhere to stringent regulatory guidelines before being approved for clinical use.
Due to their critical role in cancer treatment, anticancer drugs are in high demand worldwide. Researchers and pharmaceutical companies continually strive to develop new and more effective APIs in this category to enhance treatment outcomes and minimize side effects. The ongoing advancements in the field of anticancer drug development offer hope for improved cancer therapies and better patient outcomes.
