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Avasopasem manganese
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Looking for Avasopasem manganese API 435327-40-5?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Avasopasem manganese. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Avasopasem manganese
- Synonyms:
- Cas Number:
- 435327-40-5
- DrugBank number:
- DB16354
- Unique Ingredient Identifier:
- EY1WA413UL
General Description:
Avasopasem manganese, identified by CAS number 435327-40-5, is a notable compound with significant therapeutic applications. Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide dismutase (SOD) being investigated for the reduction of radiation-induced severe oral mucositis. This drug has potential application for radiation-induced esophagitis and oral mucositis, in addition to being currently tested against COVID-19.
Mechanism of Action:
Avasopasem manganese functions by: Avasopasem manganese is a superoxide dismutase mimetic that rapidly and selectively converts superoxide to hydrogen peroxide and oxygen in order to protect normal tissue from radiation therapy-induced damage. This drug is currently being investigated against oral mucositis, esophagitis, and COVID-19. This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Categories:
Avasopasem manganese is categorized under the following therapeutic classes: Antioxidants, Free Radical Scavengers. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Avasopasem manganese is a type of Antioxidants
Antioxidants are a vital category of pharmaceutical Active Pharmaceutical Ingredients (APIs) that play a crucial role in preventing oxidative damage and promoting overall health. Oxidative stress occurs when there is an imbalance between the production of reactive oxygen species (ROS) and the body's antioxidant defense mechanisms.
Antioxidants function by neutralizing ROS and minimizing the potential harm they can cause to cells and tissues. This category includes a diverse range of compounds, such as vitamins (e.
g.
, vitamin C, vitamin E), minerals (e.
g.
, selenium, zinc), and phytochemicals (e.
g.
, polyphenols, flavonoids). These antioxidants can be obtained from natural sources like fruits, vegetables, and herbs, or they can be synthesized in laboratories for pharmaceutical use.
The role of antioxidants in the prevention and treatment of various diseases has been extensively studied. They have demonstrated the ability to reduce the risk of chronic diseases like cardiovascular disorders, cancer, and neurodegenerative conditions. Moreover, antioxidants exhibit anti-inflammatory properties, enhance immune function, and protect against age-related damage.
In the pharmaceutical industry, antioxidants are widely utilized as key ingredients in the formulation of drugs, dietary supplements, and cosmetic products. They contribute to the stability and shelf life of pharmaceutical preparations by preventing oxidative degradation. Antioxidant APIs are manufactured with strict quality control measures to ensure purity, efficacy, and safety.
In conclusion, antioxidants are essential pharmaceutical APIs that provide numerous health benefits. Their ability to counteract oxidative stress and protect cells from damage makes them a valuable component in the prevention and treatment of various diseases. The pharmaceutical industry relies on these antioxidants to enhance the quality and efficacy of their products, making them indispensable in the field of healthcare.
