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Nicofetamide
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Looking for Nicofetamide API 553-06-0?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Nicofetamide. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Nicofetamide
- Synonyms:
- Cas Number:
- 553-06-0
- DrugBank number:
- DB13531
- Unique Ingredient Identifier:
- 9882JU353F
General Description:
Nicofetamide is a chemical compound identified by the CAS number 553-06-0. It is known for its distinct pharmacological properties and applications.
Classification:
Nicofetamide belongs to the class of organic compounds known as stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 ) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids, classified under the direct parent group Stilbenes. This compound is a part of the Organic compounds, falling under the Phenylpropanoids and polyketides superclass, and categorized within the Stilbenes class, specifically within the None subclass.
Categories:
Nicofetamide is categorized under the following therapeutic classes: Alimentary Tract and Metabolism, Drugs for Functional Gastrointestinal Disorders, Synthetic Antispasmodics, Amides With Tertiary Amines. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Nicofetamide is a type of Antispasmodics
Antispasmodics are a category of pharmaceutical active pharmaceutical ingredients (APIs) commonly used to treat muscle spasms and cramps. They work by targeting and relaxing the smooth muscles found in various organs, including the gastrointestinal tract, urinary tract, and blood vessels.
These APIs exert their effects by inhibiting the excessive contraction of muscles, thereby relieving pain and discomfort associated with spasms. Antispasmodics can be further classified into two main types: antimuscarinics and calcium channel blockers.
Antimuscarinics, such as hyoscine butylbromide and dicyclomine, function by blocking the action of acetylcholine, a neurotransmitter that stimulates muscle contractions. By inhibiting the binding of acetylcholine to its receptors, antimuscarinics help relax the smooth muscles, particularly in the gastrointestinal tract, providing relief from conditions like irritable bowel syndrome and colic.
On the other hand, calcium channel blockers, including diltiazem and nifedipine, work by blocking the influx of calcium ions into muscle cells. This inhibition prevents the contractile proteins in the muscles from interacting, resulting in muscle relaxation. Calcium channel blockers find applications in the treatment of various conditions, including uterine spasms, coronary artery spasms, and hypertension.
Antispasmodics are available in different formulations, including tablets, capsules, and injections, allowing for flexible dosing options. They are typically prescribed by healthcare professionals and should be used under medical supervision to ensure appropriate dosage and minimize potential side effects.
In summary, antispasmodics are a vital category of pharmaceutical APIs that effectively alleviate muscle spasms and cramps. Their mechanism of action involves targeting either muscarinic receptors or calcium channels, depending on the specific type. These medications provide relief to patients suffering from various conditions involving excessive muscle contractions.
