Pinaverium API Manufacturers

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Looking for Pinaverium API 59995-65-2?

Description:
Here you will find a list of producers, manufacturers and distributors of Pinaverium. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Pinaverium 
Cas Number:
59995-65-2 
DrugBank number:
DB09090 
Unique Ingredient Identifier:
U2368VVE7O

About Pinaverium

More information about the use of: Pinaverium. Pinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders 1 and may be considered as effective first-lline therapy for patients with irritable bowel syndrome (IBS) Pinaverium bromide is the common ingredient in formulations, mostly as oral tablets. Although it is not a currently approved drug by the FDA, pinaverium is available in over 60 countries including Canada.

Check who is selling Pinaverium in the overview above.

Pinaverium is a type of Antispasmodics


Antispasmodics are a category of pharmaceutical active pharmaceutical ingredients (APIs) commonly used to treat muscle spasms and cramps. They work by targeting and relaxing the smooth muscles found in various organs, including the gastrointestinal tract, urinary tract, and blood vessels.

These APIs exert their effects by inhibiting the excessive contraction of muscles, thereby relieving pain and discomfort associated with spasms. Antispasmodics can be further classified into two main types: antimuscarinics and calcium channel blockers.

Antimuscarinics, such as hyoscine butylbromide and dicyclomine, function by blocking the action of acetylcholine, a neurotransmitter that stimulates muscle contractions. By inhibiting the binding of acetylcholine to its receptors, antimuscarinics help relax the smooth muscles, particularly in the gastrointestinal tract, providing relief from conditions like irritable bowel syndrome and colic.

On the other hand, calcium channel blockers, including diltiazem and nifedipine, work by blocking the influx of calcium ions into muscle cells. This inhibition prevents the contractile proteins in the muscles from interacting, resulting in muscle relaxation. Calcium channel blockers find applications in the treatment of various conditions, including uterine spasms, coronary artery spasms, and hypertension.

Antispasmodics are available in different formulations, including tablets, capsules, and injections, allowing for flexible dosing options. They are typically prescribed by healthcare professionals and should be used under medical supervision to ensure appropriate dosage and minimize potential side effects.

In summary, antispasmodics are a vital category of pharmaceutical APIs that effectively alleviate muscle spasms and cramps. Their mechanism of action involves targeting either muscarinic receptors or calcium channels, depending on the specific type. These medications provide relief to patients suffering from various conditions involving excessive muscle contractions.