Antituberculars
Antituberculars are a vital category of pharmaceutical active pharmaceutical ingredients (APIs) used in the treatment of tuberculosis (TB). TB is a highly contagious infectious disease caused by the bacteria Mycobacterium tuberculosis, primarily affecting the lungs but also capable of affecting other organs. Antitubercular APIs play a crucial role in eradicating and controlling this global health concern.
These APIs exhibit powerful antimicrobial properties specifically targeting Mycobacterium tuberculosis. They act by inhibiting the growth and replication of the bacteria, preventing the spread of the infection. Antitubercular APIs are often used in combination therapies to maximize efficacy and minimize the development of drug resistance.
Common antitubercular APIs include isoniazid, rifampicin, pyrazinamide, ethambutol, and streptomycin. These APIs are typically administered orally or through injectable formulations, allowing for effective delivery and distribution throughout the body.
The development and production of antitubercular APIs require stringent quality control measures to ensure safety and efficacy. Pharmaceutical companies adhere to Good Manufacturing Practices (GMP) guidelines and rigorous regulatory standards to guarantee the production of high-quality APIs.
In conclusion, antitubercular APIs play a critical role in the treatment and control of tuberculosis. By effectively targeting and inhibiting the growth of Mycobacterium tuberculosis, these APIs contribute to reducing the burden of this infectious disease worldwide. Their development and production follow strict quality control standards to ensure safe and efficacious treatment options for patients.
Name | CAS number |
---|---|
Cycloserine | 68-41-7 |
Ethambutol | 74-55-5 |
Ethionamide | 536-33-4 |
Propionamide |