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Oxilofrine
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Looking for Oxilofrine API 365-26-4?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Oxilofrine. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Oxilofrine
- Synonyms:
- 4-HMP , 4-hydroxyephedrine , Methyl synephrin , Methyl synephrine , Methylsympatol , Methylsynephrin , Methylsynephrine , Oxyephedrin , p-hydroxyephedrine
- Cas Number:
- 365-26-4
- DrugBank number:
- DB11610
- Unique Ingredient Identifier:
- F49638UBDR
General Description:
Oxilofrine, identified by CAS number 365-26-4, is a notable compound with significant therapeutic applications. Oxilofrine is used in combination with as an antitussive. It is currently marketed in Canada by Valeant under the tradename Cophylac.
Indications:
This drug is primarily indicated for: Used in combination with as an antitussive . Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Pharmacodynamics:
Oxilofrine exerts its therapeutic effects through: Oxilofrine is a sympathomimetic which increases adrenergic activity . The drug's ability to modulate various physiological processes underscores its efficacy in treating specific conditions.
Mechanism of Action:
Oxilofrine functions by: Oxilofrine is likely helps to treat cough by stimulating α1 adrenergic receptors resulting in vasoconstriction. This would serve to reduce secretion of mucus into the airway and lessen the stimulus to cough. This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Classification:
Oxilofrine belongs to the class of organic compounds known as phenylpropanes. These are organic compounds containing a phenylpropane moiety, classified under the direct parent group Phenylpropanes. This compound is a part of the Organic compounds, falling under the Benzenoids superclass, and categorized within the Benzene and substituted derivatives class, specifically within the Phenylpropanes subclass.
Categories:
Oxilofrine is categorized under the following therapeutic classes: Alcohols, Amines, Amino Alcohols, Antitussive Agents, Ethylamines, Phenethylamines, Propanolamines, Propanols. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
Experimental Properties:
Further physical and chemical characteristics of Oxilofrine include:
- Water Solubility: Partly miscible
- Melting Point: 207
Oxilofrine is a type of Antitussives
Antitussives are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used in the treatment of cough. These compounds act by suppressing or inhibiting the cough reflex, providing relief to individuals suffering from excessive or persistent coughing.
Antitussives work through various mechanisms to alleviate cough symptoms. One common approach involves targeting the central nervous system (CNS) to suppress the cough reflex. This can be achieved by modulating the activity of receptors, such as opioid receptors, in the brain. Opioid-based antitussives, such as codeine or hydrocodone, are often prescribed for cough suppression due to their effectiveness in dampening the cough reflex.
Another class of antitussives work by directly affecting the respiratory system. They typically act on the sensory nerves in the airways, reducing the sensitivity and irritability that triggers coughing. Examples of these antitussives include benzonatate and dextromethorphan. These compounds work locally in the respiratory tract to provide relief by numbing or soothing the irritated nerves.
Antitussives are available in various formulations, including tablets, capsules, syrups, and lozenges, catering to different patient needs. Their usage is widespread in both over-the-counter and prescription medications to alleviate cough symptoms caused by conditions such as the common cold, flu, allergies, or respiratory tract infections.
It is important to note that antitussives should be used as directed by healthcare professionals, as excessive or inappropriate use may lead to adverse effects or mask underlying conditions. Consulting a healthcare provider is recommended before starting any antitussive treatment, especially for individuals with pre-existing medical conditions or those taking other medications.
