Cariporide API Manufacturers
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Looking for Cariporide API 159138-80-4?
- Description:
- Here you will find a list of producers, manufacturers and distributors of Cariporide. You can filter on certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Cariporide
- Synonyms:
- Cas Number:
- 159138-80-4
- DrugBank number:
- DB06468
- Unique Ingredient Identifier:
- 7E3392891K
General Description:
Cariporide is a chemical compound identified by the CAS number 159138-80-4. It is known for its distinct pharmacological properties and applications.
Indications:
This drug is primarily indicated for: Investigated for use/treatment in cardiac surgery. Its use in specific medical scenarios underscores its importance in the therapeutic landscape.
Mechanism of Action:
Cariporide functions by: Cariporide is a selective sodium-hydrogen antiporter inhibitor. The sodium-hydrogen exchanger is an importatn player in the pathophysiology of myocardial ischemia-referfusion injury. The accumulation of hydrogen ions in the myocyte cytoso; during ischemia creates a proton gradiant that promote the efflux of hydrogen ions in exchange for the influx of sodium ions. This sodium buildup can secondary activates the sodium-calcium exchanger to operate in the reverse mode, resulting in a net calcium accumulation in myocyte cytosol, which leads to dysfunction and cell death. By inhibiting sodium-hydrogen exchange, Cariporide can prevent the accumulation of calcium in cytosol, therefore reduce the infarct size. This mechanism highlights the drug's role in inhibiting or promoting specific biological pathways, contributing to its therapeutic effects.
Classification:
Cariporide belongs to the class of organic compounds known as aromatic monoterpenoids. These are monoterpenoids containing at least one aromatic ring, classified under the direct parent group Aromatic monoterpenoids. This compound is a part of the Organic compounds, falling under the Lipids and lipid-like molecules superclass, and categorized within the Prenol lipids class, specifically within the Monoterpenoids subclass.
Categories:
Cariporide is categorized under the following therapeutic classes: Amidines, Antiarrhythmic agents, Cardiovascular Agents, Potential QTc-Prolonging Agents, QTc Prolonging Agents, Sulfur Compounds. These classifications highlight the drug's diverse therapeutic applications and its importance in treating various conditions.
